Serum Beta-Defensin-2 is a biomarker for psoriasis but not subclinical atherosclerosis: Role of IL17a, PI-3 kinase and Rac1

CONCLUSIONS: Our findings expand on the potential role of BD2 as a tractable biomarker in psoriasis patients and describes the role of an IL-17A-PI3-kinase/Rac signaling axis in regulating BD2 levels in keratinocytes.PMID:38646149 | PMC:PMC11031204 | DOI:10.1002/jvc2.278

Source: Atherosclerosis - April 22, 2024 Category: Cardiology Authors: C J Pantoja H Li J Rodante A Keel A V Sorokin A Svedbom H L Teague M Stahle N N Mehta M P Playford Source Type: research