Green synthesis for diverse bioactive benzo-fused spiroindolines through DBU-catalysed post-Ugi double cyclization

Chem. Commun., 2024, Accepted Manuscript DOI: 10.1039/D4CC00846D, CommunicationShuang Zhao, Mengxiao Chen, Wenlu Zhou, Dan Ni, Zhenghua Li, Shenyou Nie, Yi He A metal-free protocol utilizing DBU catalysis for post-Ugi amide-ester exchange and Conia-ene double cyclization has successfully developed, allowing the synthesis of diverse highly functionalized cycloimide-fused spiroindolines with anti-cancer activities under... The content of this RSS Feed (c) The Royal Society of Chemistry
Source: RSC - Chem. Commun. latest articles - Category: Chemistry Authors: Source Type: research