Radiation-associated changes in saliva composition of head and neck cancer patients: A systematic review

Head and neck squamous cell cancer accounts for approximately 4.5% of the newly diagnosed malignancies worldwide, with over 878,000 new cases in 2020 (including lip cancer) [1]. The incidence is rising, especially due to HPV associated head and neck cancer and is expected to increase by 30% until 2030 [2]. Compared to non-HPV related head and neck cancer, often induced by heavy alcohol consumption and/or smoking, the HPV-positive patients usually have a good prognosis after therapy, even with advanced stages of disease at diagnosis.
Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Review Article Source Type: research