Pediatric thyroid side effects of immune checkpoint inhibitors

Trends Endocrinol Metab. 2024 Apr 17:S1043-2760(24)00085-7. doi: 10.1016/j.tem.2024.04.002. Online ahead of print.ABSTRACTImmune checkpoint inhibitors (ICIs) are associated with multiple endocrine side effects, including thyroid disfunctions. In addition, the efficacy and safety profiles of ICIs in the pediatric population need clarification. Here, we discuss the main evidence regarding the efficacy and thyroid toxicities of ICIs in children.PMID:38637222 | DOI:10.1016/j.tem.2024.04.002
Source: Trends in Endocrinology and Metabolism: TEM - Category: Endocrinology Authors: Source Type: research