Controlling Nanoparticle Distance by On ‐Surface DNA‐Origami Folding

This study describes a novel approach that combines top-down lithography with bottom-up DNA origami techniques to control folding of the DNA origami with the adsorption on pre-patterned surfaces. Using this approach, tunable plasmonic dimer nano-arrays are fabricated on a silicon surface. This involves employing electron beam lithography to create adsorption sites on the surface and utilizing self-organized adsorption of DNA origami functionalized with two gold nanoparticles (AuNPs). The desired folding of the DNA origami helices can be controlled by the size and shape of the adsorption sites. This approach can for example be used to tune the center-to-center distance of the AuNPs dimers on the origami template. To demonstrate this technique's efficiency, the Raman signal of dye molecules (carboxy tetramethylrhodamine, TAMRA) coated on the AuNPs surface are investigated. These findings highlight the potential of tunable DNA origami-based plasmonic nanostructures for many applications.

Source: Small - April 18, 2024 Category: Nanotechnology Authors: Zhe Liu, Zunhao Wang, Jannik Guckel, Ziba Akbarian, Tim J. Seifert, Daesung Park, Uta Schlickum, Rainer Stosch, Markus Etzkorn Tags: Research Article Source Type: research