Tailorable optical properties of polymer nanodots for triple-mode fluorescence detection of nucleic acids

We present a triple-mode nanosensor platform for nucleic acid detection utilizing fluorescence anisotropy and Förster resonance energy transfer (FRET) strategies. The self-assembled nanoprobes serve as mass amplifiers, nanoquenchers, or nanodonors, exhibiting high FRET efficiencies (64.4-86.5%) and demonstrating excellent detection capabilities in DNA and microRNA analysis.PMID:38629242 | DOI:10.1039/d4cc01327a

Source: Chemical Communications - April 17, 2024 Category: Chemistry Authors: Chao Guo Enna Cui Mengxiao Wang Xuan Liu Yanyan Yu Xiaojiang Xie Dongzhi Yang Source Type: research