Associations between mitochondrial copy number, exercise capacity, physiologic cost of walking, and cardiac strain in young adult survivors of childhood cancer

ConclusionsIncreased mtDNA-CN is associated with decreased odds of abnormal cardiac function in childhood cancer survivors.Implications for Cancer SurvivorsThese findings demonstrate a potential role for mtDNA-CN as a biomarker of early cardiac dysfunction in this population.
Source: Journal of Cancer Survivorship - Category: Cancer & Oncology Source Type: research