Seeing through the density of dense deposit disease

This study presents the novel finding that large accumulations of apolipoprotein E are present in the deposits of DDD, as revealed by mass spectroscopy and confirmed by both confocal microscopy and immunohistochemistry. The findings suggest a new modality for diagnosis of DDD and introduce potential new mechanisms for understanding DDD pathophysiology.
Source: Kidney International - Category: Urology & Nephrology Authors: Tags: Commentary Source Type: research