GSE246899 Effect of knockout ERO1 α on gene expression in mTORC1 activated mouse embryonic fibroblasts

Contributors : Zixi Wang ; Huaiyuan Zong ; Xiaojun ZhaSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusEndoplasmic reticulum oxidoreductase 1 alpha (ERO1 α) is an endoplasmic reticulum stress–related gene, which improves cell perseverance against challenges of high levels of protein misfolding during endoplasmic reticulum stress by retaining good activity of oxidative protein folding. Numerous studies have shown abnormal expression of ERo1α in va rious diseases, but its downstream target are not fully understood. Our work will help in the elucidation of the downstream molecular mechanism of ERO1α.

Source: GEO: Gene Expression Omnibus - April 17, 2024 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research