Crafty mimicry grants nuclear pore entry to HIV

Cell Host Microbe. 2024 Apr 10;32(4):441-442. doi: 10.1016/j.chom.2024.03.004.ABSTRACTThe size of the nuclear pore should, in principle, prevent HIV-1 entry. However, HIV-1 capsid is able to gain nuclear pore entry. In a recent issue of Nature, Fu et al. and Dickson et al. demonstrate that the HIV-1 capsid mimics the nuclear transport protein karyopherins to access host nuclei.PMID:38604120 | DOI:10.1016/j.chom.2024.03.004

Source: Cell Host and Microbe - April 11, 2024 Category: Microbiology Authors: Keesiang Lim Masaharu Hazawa Richard W Wong Source Type: research