Deguelin inhibits the proliferation of human multiple myeloma cells by inducing apoptosis and G2/M cell cycle arrest: Involvement of Akt and p38 MAPK signalling pathway

In conclusion, deguelin treatment, when applied in vitro, induced apoptotic cell death and resulted in mitotic cessation at the G2/M phase through modulation of cell cycle regulatory mRNAs in multiple myeloma cells.PMID:38554386 | DOI:10.2478/acph-2024-0003

Source: Acta Pharmaceutica - March 30, 2024 Category: Drugs & Pharmacology Authors: Kening Sun Ping Chen Liang Zhang Zhidong Lu Qunhua Jin Source Type: research