Comparison of the solid-phase red cell adherence assay and tube method for detection and identification of red blood cell antibodies

CONCLUSIONS: To our knowledge, this is the first robust, 15-year study comparing methodologic sensitivity to detect clinically significant alloantibodies. The incidence of discordant results between PEG-IAT and the solid-phase technique was low. Among discordant samples, anti-Jka was commonly detected using the solid-phase method but not with the PEG-IAT. In contrast, anti-E was commonly detected by PEG-IAT but not by the solid-phase method.PMID:38607807 | DOI:10.1093/ajcp/aqae035
Source: American Journal of Clinical Pathology - Category: Pathology Authors: Source Type: research