Statistical Techniques to Assess Publication Integrity in Groups of Randomised Trials: A Narrative Review

ObjectiveTo describe statistical tools available for assessing publication integrity of groups of randomised controlled trials (RCTs)Study DesignNarrative reviewResultsFreely available statistical tools have been developed that compare the observed distributions of baseline variables with the expected distributions that would occur if successful randomisation occurred. For continuous variables, the tools assess baseline means, baseline p-values, and the occurrence of identical means and/or SD. For categorical variables, they assess baseline p-values, frequency counts for individual or all variables, numbers of trial participants randomised or withdrawing, and compare reported with independently calculated p-values.
Source: Journal of Clinical Epidemiology - Category: Epidemiology Authors: Tags: Original Article Source Type: research