Mitotic gene regulation by the N-MYC-WDR5-PDPK1 nexus

During mitosis the cell depends on proper attachment and segregation of replicated chromosomes to generate two identical progeny. In cancers defined by overexpression or dysregulation of the MYC oncogene this pro...

Source: BMC Genomics - April 11, 2024 Category: Genetics & Stem Cells Authors: Sarah A. Streeter, Alexandria G. Williams, James R. Evans, Jing Wang, Alissa D. Guarnaccia, Andrea C. Florian, Rafet Al-Tobasei, Qi Liu, William P. Tansey and April M. Weissmiller Tags: Research Source Type: research