Neurofilaments as biomarkers in neurological disorders — towards clinical application

Nature Reviews Neurology, Published online: 12 April 2024; doi:10.1038/s41582-024-00955-xNeurofilaments have been validated as specific body fluid biomarkers of neuro-axonal injury. In this Review, Khalil and colleagues provide an update on the structure and function of neurofilaments, analytical approaches and challenges in different clinical contexts, and progress towards clinical application of neurofilaments as a biomarker in various neurological disorders.

Source: Nature Reviews Neurology - April 12, 2024 Category: Neurology Authors: Michael Khalil Charlotte E. Teunissen Sylvain Lehmann Markus Otto Fredrik Piehl Tjalf Ziemssen Stefan Bittner Maria Pia Sormani Thomas Gattringer Samir Abu-Rumeileh Simon Thebault Ahmed Abdelhak Ari Green Pascal Benkert Ludwig Kappos Manuel Comabella Hayr Source Type: research