A Clinical Trial of High Dose Growth Hormone in a Patient with a Dominant Negative Growth Hormone Receptor Mutation
CONCLUSIONS: A precision medicine approach of extremely high dose GH was able to overcome GH resistance in a patient with a dominant-negative variant in the GH receptor resulting in elevated GH binding protein levels.PMID:38597155 | DOI:10.1210/clinem/dgae244
Source: The Journal of Clinical Endocrinology and Metabolism - Category: Endocrinology Authors: Nadia Merchant Lisa Houchin Kimberly Boucher Andrew Dauber Source Type: research