Unresectable biliary tract cancer: current and future systemic therapy

For decades, treatment of advanced biliary tract cancer (BTC) was confined to the use of chemotherapy. In recent years however, the number of therapeutic options available for patients with unresectable BTC have drastically increased, with immunotherapy and targeted treatment gradually joining the ranks of guideline-recommended treatment regimens.The aim of the present review is to summarise the current knowledge on unresectable BTC focusing on epidemiology, anatomical distribution and current strategies for systemic treatment.

Source: European Journal of Cancer - April 11, 2024 Category: Cancer & Oncology Authors: Danmei Zhang, Klara Dorman, C. Benedikt Westphalen, Michael Haas, Steffen Ormanns, Jens Neumann, Max Seidensticker, Jens Ricke, Enrico N. De Toni, Frederick Klauschen, Hana Alg ül, Timo Reisländer, Stefan Boeck, Volker Heinemann Tags: Review Source Type: research