Single-cell profiling reveals kidney CD163+ dendritic cell participation in human lupus nephritis

Conclusion
The intricate interplay involving DC3s, T cells and tubular epithelial cells within kidneys may substantially contribute to LN pathogenesis. The enumeration of renal DC3 holds potential as a valuable stratification feature for guiding LN patient treatment decisions in clinical practice.

Source: Annals of the Rheumatic Diseases - April 11, 2024 Category: Rheumatology Authors: Chen, W., Jin, B., Cheng, C., Peng, H., Zhang, X., Tan, W., Tang, R., Lian, X., Diao, H., Luo, N., Li, X., Fan, J., Shi, J., Yin, C., Wang, J., Peng, S., Yu, L., Li, J., Wu, R.-Q., Kuang, D.-M., Shi, G.-P., Zhou, Y., Wang, F., Jiang, X. Tags: ARD, Autoimmunity Source Type: research