EPO promotes the progression of rheumatoid arthritis by inducing desialylation via increasing the expression of neuraminidase 3

Conclusion
EPO, as a proinflammatory factor, accelerates the process of RA through transcriptional upregulation of the expression of NEU3 by JAK2/STAT5 pathway.

Source: Annals of the Rheumatic Diseases - April 11, 2024 Category: Rheumatology Authors: Wu, G., Cao, B., Zhai, H., Liu, B., Huang, Y., Chen, X., Ling, H., Ling, S., Jin, S., Yang, X., Wang, J. Tags: Open access, ARD, Rheumatoid arthritis Source Type: research