The impact of intermittent hypoxemia on type 1 retinopathy of prematurity in preterm infants

CONCLUSIONS: For most analyses there was no significant association between IH and Type 1 ROP adjusting for GA and BW. However, infants with longer IH duration during the second month of life had higher risk for Type 1 ROP.IMPACT: The relationship and predictive ability of intermittent hypoxemia (IH) on retinopathy of prematurity (ROP) is controversial. This study shows no significant association between IH events and Type 1 ROP after adjusting for gestational age (GA) and birth weight (BW), except for cumulative IH of longer duration in the second month of life. In this cohort, IH does not provide a statistically significant improvement in ROP prediction over GA and BW. This study is the first to assess the cumulative impact of IH measures on Type 1 ROP. Interventions for reducing IH duration during critical postnatal periods may improve ROP outcomes.PMID:38600299 | DOI:10.1038/s41390-024-03169-5

Source: Pediatric Research - April 10, 2024 Category: Pediatrics Authors: Samaneh Rabienia Haratbar Li Chen Qiang Cheng Dara Singh Faraneh Fathi Mehrana Mohtasebi Xuhui Liu Abhijit Patwardhan Prasad Bhandary Henrietta S Bada Guoqiang Yu Elie G Abu Jawdeh Source Type: research