Progressive changes in the protein expression profile of alveolar septa in early-stage lung adenocarcinoma

CONCLUSIONS: FAP-positive fibroblasts may contribute to tumor stroma formation in early-stage lung adenocarcinoma, and this could influence the development of therapeutic strategies targeting FAP-positive CAFs for disrupting extracellular matrix formation.PMID:38600426 | DOI:10.1007/s10147-024-02507-1

Source: Clinical Lung Cancer - April 10, 2024 Category: Cancer & Oncology Authors: Toru Kimura Takashi Akazawa Yu Mizote Harumi Nakamura Miki Sakaue Tomohiro Maniwa Yasushi Shintani Keiichiro Honma Hideaki Tahara Jiro Okami Source Type: research