Impact of Physiological Fluctuations of Sex Hormones During the Menstrual Cycle on Glucose Metabolism and the Gut Microbiota
Exp Clin Endocrinol Diabetes DOI: 10.1055/a-2273-5602Diabetes mellitus is one of the most prevalent chronic diseases. Previous studies
have shown differences in glucose metabolism between males and females.
Moreover, difficulties in medication adherence have been reported in females
with type 2 diabetes. These observations are believed to be caused by
fluctuations in sex hormone concentrations during the menstrual cycle.
Furthermore, gut microbiota is linked to female host metabolism and sex hormone
production. Understanding the interactions between fluctuating hormone
concentrations during the menstrual cycle, gut microbiota, and glucose
metabolism in humans is significant because of the increasing prevalence of
diabetes and the consequent need to expand preventive efforts. A literature
search was performed to determine and summarize the existing evidence, deduce
future research needs to maintain female health, and investigate the
relationship between the physiological menstrual cycle and glucose metabolism.
Studies from 1967 to 2020 have already examined the relationship between
variations during the menstrual cycle and glucose metabolism in healthy female
subjects using an oral-glucose tolerance test or intravenous glucose tolerance
test. However, the overall number of studies is rather small and the results are
...
Source: Experimental and Clinical Endocrinology and Diabetes - Category: Endocrinology Authors: Schieren, Alina Koch, Sandra Pecht, Tal Simon, Marie-Christine Tags: Review Source Type: research