Spatially Resolved Microglia/Macrophages in Recurrent Glioblastomas Overexpress Fatty Acid Metabolism and Phagocytic Genes

CONCLUSION: Tumor-associated microglia/macrophages in recurrent GBM overexpress genes involved in fatty acid/lipid metabolism. Further investigation is needed to fully delineate the role of PLD phospholipases in GBM progression.PMID:38534921 | PMC:PMC10968993 | DOI:10.3390/curroncol31030088

Source: Current Oncology - March 27, 2024 Category: Cancer & Oncology Authors: Akshitkumar M Mistry Jonah Daneshmand SeonYeong Jamie Seo Norman L Lehman Donald M Miller Dylan A Goodin Hermann B Frieboes Joseph Chen Adrianna Masters Brian J Williams Kavitha Yaddanapudi Source Type: research