Analytical method development, identification, and characterization of stress degradation products of idelalisib by ultrahigh-performance liquid chromatography with photodiode array and ultrahigh-performance liquid chromatography with electrospray ionization quadrupole time-of-flight mass spectrometry studies

CONCLUSIONS: A UHPLC-PDA method was developed and validated for idelalisib. Four degradation products of idelalisib were revealed through UHPLC/ESI-QTOFMS studies, and corresponding degradation pathways were postulated for the same.PMID:38591150 | DOI:10.1002/rcm.9745

Source: Rapid Communications in Mass Spectrometry : RCM - April 9, 2024 Category: Chemistry Authors: Marella Mahesh Alka Bali Tanvi Gupta Source Type: research