Atrioventricular Optimization Improves Cardiac Resynchronization Response in Patients with Long Interventricular Electrical Delays: A Pooled Analysis of the SMART-AV and SMART-CRT Trials

The utility of atrioventricular (AV) optimization (AVO) algorithms remains in question. A substudy of the SMART-AV trial found patients with prolonged interventricular (RV-LV) delays ≥70 ms were more likely to benefit from CRT with AVO. The SMART-CRT trial evaluated AVO based on these results, but the study was underpowered.

Source: Heart Rhythm - April 9, 2024 Category: Cardiology Authors: Michael R. Gold, Angelo Auricchio, Christophe Leclercq, Nicholas Wold, Kenneth M. Stein, Kenneth A. Ellenbogen Source Type: research