Randomized Crossover Comparison of the Short‐Term Efficacy and Safety of Single Half‐Dose Silodosin and Tamsulosin Hydrochoride in Men With Lower Urinary Tract Symptoms Secondary to Benign Prostatic Hyperplasia

ConclusionSingle half‐dose silodosin has a similar efficacy to full‐dose tamsulosin in Japanese men with LUTS/BPH and thus, may represent an effective, safe, and affordable treatment option.
Source: LUTS: Lower Urinary Tract Symptoms - Category: Urology & Nephrology Authors: Tags: ORIGINAL ARTICLE Source Type: research

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ConclusionsThe present study characterizes metabolic disturbances in both tissue and biofluid samples during PCa progression and provides potential diagnostic biomarkers and therapeutic targets for PCa.
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
AbstractDespite effective medications, rates of uncontrolled glucose levels in type 2 diabetes remain high. We aimed to test the utility of machine learning applied to big data in identifying the potential role of concomitant drugs not taken for diabetes which may contribute to lowering blood glucose. Success in controlling blood glucose was defined as achieving HgA1c levels  
Source: Pharmacology Research and Perspectives - Category: Drugs & Pharmacology Authors: Tags: ORIGINAL ARTICLE Source Type: research
Prostate Cancer and Prostatic Diseases, Published online: 18 November 2019; doi:10.1038/s41391-019-0187-5Water vapor thermal therapy to alleviate catheter-dependent urinary retention secondary to benign prostatic hyperplasia
Source: Prostate Cancer and Prostatic Diseases - Category: Urology & Nephrology Authors: Source Type: research
ConclusionsTortuosity of pelvic arteries was more frequent in older patients and predicted worse technical outcomes of PAE. PA origin from obturator artery was associated with lower DAP and fluoroscopy time, especially compared with PA origin from superior vesical artery. Interventionalist experience showed significant influence on technical outcome.
Source: Journal of Vascular and Interventional Radiology - Category: Radiology Source Type: research
Source: BMJ - Category: General Medicine Source Type: research
To present outcomes for prostatic artery embolization (PAE) to treat urinary retention and gross prostatic hematuria in non-index benign prostatic hyperplasia (BPH) patients.
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
ConclusionPeriodontal disease is significantly and positively associated with an increased risk of benign prostatic hyperplasia. Further validation studies should be performed to explore the relationship between periodontal treatment and benign prostate hyperplasia.
Source: Military Medical Research - Category: International Medicine & Public Health Source Type: research
Tm:YAG laser operates at a wavelength of 1940-2013 nm in a continuous wave mode, which enables smooth incision and rapid vaporization of prostatic tissue, with a shallow penetration of only 0.2 mm. These characteristics make Tm:YAG a versatile laser, allowing the surgeon to perform resection, vaporization, and vapoenucleation. This systematic review aims to summarize the current evidence of safety and efficacy, long-term durability, impact on sexual function following Tm:YAG laser enucleation and vapoenucleation of the prostate and to compare the outcomes of these procedures versus other surgical treatments of benign prostatic hyperplasia.
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
Authors: Nan LB, Yin XT, Gao JP Abstract BACKGROUND The aim of this study was to investigate the diagnostic value of (F/T)/PSAD for prostate cancer detection in the Chinese population. MATERIAL AND METHODS Data were collected retrospectively from patients with prostate cancer or benign prostatic hyperplasia from July 2009 to September 2014. SPSS 19.0 software was used for the receiver operating characteristic curve (ROC), and calculating sensitivity, specificity, and positive predictive values (PPV) and negative predictive values (NPV), respectively. Comparison of the area under ROC (AUC) was performed using the Me...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Authors: Danilov SM, Kadrev AV, Kurilova OV, Tikhomirova VE, Kryukova OV, Mamedov VN, Kamalov DM, Danilova NV, Okhobotov DA, Gayfullin NM, Evdokimov VV, Alekseev BJ, Kost OA, Samokhodskaya LM, Kamalov AA Abstract Epithelial cells of prostate express significant level of ACE and, as a result, seminal fluid has 50-fold more ACE than plasma. The substitution of highly specialized prostate epithelial cells by tumor cells results in dramatic decrease in ACE production in prostate tissues. We performed detailed characterization of ACE status in prostate tissues from patients with benign prostate hyperplasia (BPH) and pro...
Source: Oncotarget - Category: Cancer & Oncology Tags: Oncotarget Source Type: research
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