Association between the neutrophil ‐to‐lymphocyte ratio and intravesical prostatic protrusion in men with benign prostatic hyperplasia
AbstractObjectiveTo analyze the association between neutrophil ‐to‐lymphocyte ratio (NLR) and intravesical prostatic protrusion (IPP) in men with benign prostatic hyperplasia.MethodsTwo hundred and fifty men aged>50  years who presented with lower urinary tract symptoms at our institution between 2014 and 2018 were analyzed. Pearson's method was used for analysis of the correlation between NLR and IPP. Multivariate logistic regression analysis was used to identify predictors of IPP. Further analysis according to total prostate volume (TPV) was performed.ResultsThe NLR correlated positively with IPP (Pearson's r = 0.459,P
Source: LUTS: Lower Urinary Tract Symptoms - September 15, 2019 Category: Urology & Nephrology Authors: Mun Su Chung, Yun Jung Yang, Seung Hwan Lee, Byung Il Yoon Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
LUTS: Lower Urinary Tract Symptoms, Volume 11, Issue 4, Page 175-175, September 2019. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 11, 2019 Category: Urology & Nephrology Tags: ISSUE INFORMATION Source Type: research

Hyperlipidemia as a risk factor for discontinuation of prescribed antimuscarinics among geriatric overactive bladder patients
LUTS: Lower Urinary Tract Symptoms, Volume 11, Issue 4, Page 255-256, September 2019. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 11, 2019 Category: Urology & Nephrology Authors: Yu ‐Chen Chen, Hao‐Wei Chen, Yung‐Shun Juan Tags: LETTER TO THE EDITOR Source Type: research

High incidence of lower urinary tract dysfunction in women with recurrent urinary tract infections
AbstractThe aim of this study was to evaluate lower urinary tract dysfunction (LUTD) in women with recurrent urinary tract infections (UTIs). One hundred consecutive female patients with recurrent UTIs who underwent videourodynamic study (VUDS) were included. Another 25 women free from recurrent UTIs served as controls. All the underlying diseases, urine analysis and culture results, VUDS findings, and treatment outcomes of voiding dysfunction were carefully reviewed and analyzed. The mean age of the recurrent UTIs patients was 64.0 ± 16.0 years. Storage and voiding dysfunctions were found in 90 (90%) patient...
Source: LUTS: Lower Urinary Tract Symptoms - August 29, 2019 Category: Urology & Nephrology Authors: Ping ‐Jui Lee, Hann‐Chorng Kuo Tags: ORIGINAL ARTICLE Source Type: research

Association of midline prostatic cysts and lower urinary tract symptoms: A case ‐control analysis of 606 transrectal ultrasound findings
ConclusionsThe presence of MPCs is not an independent factor for moderate to severe LUTS, and the size of the MPCs does not have any correlation to LUTS scores either. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - August 29, 2019 Category: Urology & Nephrology Authors: Bumsoo Park, Sung ‐Ho Ju, Seol Ho Choo Tags: ORIGINAL ARTICLE Source Type: research

Influence of alpha ‐adrenoceptor antagonists therapy on stool form in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia
ConclusionsThis study suggests that silodosin was associated with increased digestive symptoms such as diarrhea and loose stools. Therefore, oral drugs for BPH need to be selected by taking into consideration the possibility of digestive symptoms including both the state and type of stools. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - August 29, 2019 Category: Urology & Nephrology Authors: Seiji Matsumoto, Sachiko Kasamo, Kazumi Hashizume Tags: ORIGINAL ARTICLE Source Type: research

Cognitive burden and polypharmacy in elderly Japanese patients treated with anticholinergics for an overactive bladder
This study aimed to investigate the cognitive burden and polypharmacy in elderly patients treated with anticholinergics for an overactive bladder. We conducted a retrospective study of patients with an overactive bladder receiving treatment at two hospitals in Japan (Nara Medical University Hospital and Saiseikai Nara Hospital). Prescription data were collected from the medical records of the patients registered between January 2013 and April 2014. The Anticholinergic Cognitive Burden Scale was used to estimate the severity of the anticholinergic effects on the cognition of each patient. We collected the prescription data ...
Source: LUTS: Lower Urinary Tract Symptoms - August 28, 2019 Category: Urology & Nephrology Authors: Takako Shiota, Kazumasa Torimoto, Masahiro Okuda, Ryo Iwata, Hiromi Kumamoto, Makito Miyake, Akihide Hirayama, Nobumichi Tanaka, Kiyohide Fujimoto Tags: ORIGINAL ARTICLE Source Type: research

Evaluation of the effect of a new method on the pelvic organ prolapse symptoms
ConclusionThis new method of postural or positional inversion leads to a greater improvement in symptoms of pelvic organ prolapse. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - August 26, 2019 Category: Urology & Nephrology Authors: Zahra Gorji, Abbas A. Pourmomeny, Maryam Hajhashemy Tags: ORIGINAL ARTICLE Source Type: research

Predictive factors for recovery of voiding function after transurethral prostate surgery in men with small prostate volume and very low detrusor contractility
This study aims to investigate effectiveness and predictors of voiding function recovery after prostate surgery in patients with DU.MethodsMale patients with DU and small total prostate volume (TPV,
Source: LUTS: Lower Urinary Tract Symptoms - August 20, 2019 Category: Urology & Nephrology Authors: Shu ‐Yu Wu, Hann‐Chorng Kuo Tags: ORIGINAL ARTICLE Source Type: research

Further characterization of a novel EP2 and EP3 receptor dual agonist, ONO ‐8055, on lower urinary tract function in normal and lumbar canal stenosis rats
ConclusionsThis agonist did not augment bladder contractility or urethral relaxation in normal rats. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - August 20, 2019 Category: Urology & Nephrology Authors: Noritoshi Sekido, Jun Kida, Takeya Otsuki, Hiroko Mashimo, Hidekazu Matsuya, Hiroki Okada Tags: ORIGINAL ARTICLE Source Type: research

Efficacy of Tadalafil Therapy and Changes in Oxidative Stress Levels in Male Patients with Lower Urinary Tract Symptoms and Overactive Bladder
The objective findings were assessed using uroflowmetry. Oxidative stress was assessed by determining urinary levels of 8‐hydroxy‐2′‐deoxyguanosine (8‐OHdG) levels with an adjustment for urinary creatinine (CR) concentration.ResultsAfter tadalafil administration, total and individual indices of the OABSS assessment showed significant improvement. In addition, total storage and voiding symptoms that contributed to the IPSS were also significantly improved. The voided volume was increased, and the maximum flow rate was improved after tadalafil treatment (P = .002 and
Source: LUTS: Lower Urinary Tract Symptoms - August 13, 2019 Category: Urology & Nephrology Authors: Tomohiro Matsuo, Yasuyoshi Miyata, Kyohei Araki, Yuta Mukae, Asato Otsubo, Kojiro Ohba, Hideki Sakai Tags: ORIGINAL ARTICLE Source Type: research

The autologous pubovaginal fascial sling: An update in 2019
AbstractThe contemporary management of stress urinary incontinence (SUI) has seen renewed interest in the use of autologous fascia for the formation of a retropubic suburethral sling. Traditionally, it has been used in only the most severe of incontinence cases, such as those women with intrinsic sphincter deficiency, or in patients requiring concomitant reconstructive procedures. In the current climate surrounding transvaginal mesh, many doctors and patients are shying away from the less morbid synthetic midurethral sling. International literature has demonstrated that the fascial sling is a safe and efficacious procedure...
Source: LUTS: Lower Urinary Tract Symptoms - August 13, 2019 Category: Urology & Nephrology Authors: Sophie Plagakis, Vincent Tse Tags: REVIEW ARTICLE Source Type: research

Efficacy and safety of 25 and 50 μg desmopressin orally disintegrating tablets in Japanese patients with nocturia due to nocturnal polyuria: Results from two phase 3 studies of a multicenter randomized double‐blind placebo‐controlled parallel‐group development program
This study assessed the efficacy and safety of desmopressin orally disintegrating tablets (ODTs) in Japanese males (50 and 25  μg) and females (25 μg) with nocturia due to nocturnal polyuria (NP). Two Phase 3 randomized double‐blind placebo‐controlled studies of 342 males and 190 females with nocturia due to NP were conducted. The primary endpoint was change from baseline in mean number of nocturnal voids. In add ition, time to first awakening to void, nocturnal urine volume, NP index (NPI), and quality of life were assessed during a 12‐week treatment period. In males, 50 and 25 μg desmo...
Source: LUTS: Lower Urinary Tract Symptoms - August 9, 2019 Category: Urology & Nephrology Authors: Osamu Yamaguchi, Kristian V. Juul, Ali Falahati, Toru Yoshimura, Futoshi Imura, Mikiya Kitamura Tags: ORIGINAL ARTICLE Source Type: research

Mirabegron causes vesical and urethral relaxation in rats with spinal cord injury
AbstractThe effects of solifenacin and mirabegron on vesical and urethral function were compared in rats with or without spinal cord injury (SCI). Isovolumetric cystometry and urethral pressure recording were initially performed in intact rats. Then, the bladder neck was ligated under urethane anesthesia, after which a catheter was inserted through the bladder dome for isovolumetric cystometry and another catheter was inserted into the urethra to measure urethral pressure. Solifenacin (0.03 –3 mg/kg) or mirabegron (0.03–3 mg/kg) was injected intravenously, and bladder and urethral activity were recorded. To cre...
Source: LUTS: Lower Urinary Tract Symptoms - August 7, 2019 Category: Urology & Nephrology Authors: Kimio Sugaya, Saori Nishijima, Katsumi Kadekawa, Katsuhiko Noguchi, Tomoyuki Ueda, Hideyuki Yamamoto Tags: ORIGINAL ARTICLE Source Type: research

Prevalence, potential risk factors, and symptomatic bother of lower urinary tract symptoms during and after pregnancy
ConclusionsLUTS were much more prevalent during than after pregnancy, with nocturia and frequency being the most prevalent. Moderate or severe bother was more common during pregnancy than after pregnancy. CS was associated with a decreased prevalence both of storage and voiding LUTS after delivery. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - July 18, 2019 Category: Urology & Nephrology Authors: Zhiyi Li, Tao Xu, Lei Zhang, Lan Zhu Tags: ORIGINAL ARTICLE Source Type: research

Validation of a real ‐time bladder sensation meter during oral hydration in healthy adults: Repeatability and effects of fill rate and ultrasound probe pressure
ConclusionsThis study demonstrated repeatability of real ‐time bladder sensation during a two‐fill oral hydration protocol with ultrasound. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - July 12, 2019 Category: Urology & Nephrology Authors: Derek Sheen, Hiren Kolli, Anna S. Nagle, Zachary Cullingsworth, Naomi N. Vinod, Hameeda A. Naimi, Stefan G. De Wachter, Suzanne E. Mazzeo, Lynn Stothers, John E. Speich, Adam P. Klausner Tags: ORIGINAL ARTICLE Source Type: research

Underactive bladder in aging rats is associated with a reduced number of serotonin ‐expressing cells in the urethra and is improved by serotonin application to the urethra
AbstractThe aim of this study was to determine whether aging ‐related detrusor underactivity (DU) involves a decrease in 5‐hydroxytryptamine (5‐HT‐positive)‐expressing urethral cells and whether 5‐HT stimulation of urethral sensory fibers improves detrusor function. Cystometries were performed in young (6 months) and aged (18–24 months) female Wistar rats. Aged rats with voiding contractions (VC) that were 2SD below the mean of those in young rats were considered to have DU. Bladder voiding efficiency (BVE) was calculated during saline or 5‐HT solution cystometries. Rats were perfusion‐fixed wi...
Source: LUTS: Lower Urinary Tract Symptoms - June 28, 2019 Category: Urology & Nephrology Authors: Ana Coelho, Ana Charrua, Raquel Oliveira, Helena Cavaleiro, C élia D. Cruz, Francisco Cruz Tags: ORIGINAL ARTICLE Source Type: research

Administration of human umbilical cord blood mononuclear cells restores bladder dysfunction in streptozotocin ‐induced diabetic rats
This study evaluated the effect of human umbilical cord blood mononuclear cells (HUCB ‐MNCs) on bladder dysfunction in streptozotocin (STZ; 35 mg/kg, i.v.)‐induced diabetic rats.MethodsAdult male Sprague –Dawley rats (n = 30) were equally divided into three groups: control group, STZ‐diabetic group, and HUCB‐MNC‐treated group (1 × 106 cells). HUCB ‐MNCs were isolated by density gradient centrifugation from eight healthy donors and injected into the corpus cavenosum in STZ‐diabetic rats 4 weeks after the induction of diabetes. Studies were performed 4 weeks after ...
Source: LUTS: Lower Urinary Tract Symptoms - June 17, 2019 Category: Urology & Nephrology Authors: Ecem Kaya ‐Sezginer, Didem Yilmaz‐Oral, Serap Gur Tags: ORIGINAL ARTICLE Source Type: research

Tadalafil, a phosphodiesterase type 5 inhibitor, restores urethra and detrusor function in the initial phase of diabetes in rats
This study investigated the effects of tadalafil on the urethra and detrusor in the initial phase of diabetes in rats.MethodsThirty ‐six female Sprague‐Dawley rats were assigned to a non‐diabetes (ND), diabetes (D), or tadalafil‐treated diabetes (DT) group (n = 12 per group), with the DT group receiving oral tadalafil (2 mg/kg/d) for 7 days before the experiments. Seven weeks after diabetes induction (by a single intra peritoneal injection of streptozotocin), urethral and intravesical pressure were simultaneously recorded in vivo, whereas responses of detrusor strips to potassium chloride (30 mM), ele...
Source: LUTS: Lower Urinary Tract Symptoms - June 17, 2019 Category: Urology & Nephrology Authors: Daisuke Gotoh, Kazumasa Torimoto, Hirotaka Iwasaki, Takashi Iwamoto, Yosuke Morizawa, Shunta Hori, Makito Miyake, Nobumichi Tanaka, Akihide Hirayama, Eiichiro Nishi, Kiyohide Fujimoto Tags: ORIGINAL ARTICLE Source Type: research

Substitution urethroplasty for the treatment of male urethral stricture: Outcomes in an Australian center
ConclusionsSubstitution urethroplasty has a high success rate, durable response, and high patient satisfaction. Standardization of surveillance protocol after urethroplasty is recommended. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - May 7, 2019 Category: Urology & Nephrology Authors: Yasser Al ‐Hakeem, Amanda Chung, Belinda Chung, Vincent Tse Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
LUTS: Lower Urinary Tract Symptoms, Volume 11, Issue 3, Page 87-90, May 2019. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - April 24, 2019 Category: Urology & Nephrology Tags: ISSUE INFORMATION Source Type: research

Is trigonitis a neglected, imprecise, misunderstood, or forgotten diagnosis?
AbstractTo consolidate our understanding of “trigonitis” and its relevance in current urologic practice, we reviewed the literature on this entity. The MEDLINE, EMBASE, and Cochrane databases (1905 to present) were systematically reviewed for any English language articles addressing the following terms: trigonitis, cystitis trigoni, cysti tis cystica, squamous metaplasia, pseudomembranous trigonitis, vaginal metaplasia, infection or inflammation of the trigone, and trigonitis in recurrent urinary tract infections (rUTI). Abstracts or articles not focused on trigonitis, or those only repeating findings from othe...
Source: LUTS: Lower Urinary Tract Symptoms - April 15, 2019 Category: Urology & Nephrology Authors: Zhina Sadeghi, Gregory MacLennan, Stacy J. Childs, Philippe E. Zimmern Tags: REVIEW ARTICLE Source Type: research

Effect of ureteral stent diameter on ureteral stent ‐related symptoms
ConclusionThis is the first study to show that larger ‐diameter ureteral stents induce significantly worse urinary symptoms. Ureteral stents with smaller diameters are recommended to improve ureteral stent‐related symptoms. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - April 7, 2019 Category: Urology & Nephrology Authors: Makoto Taguchi, Kenji Yoshida, Motohiko Sugi, Hidefumi Kinoshita, Tadashi Matsuda Tags: ORIGINAL ARTICLE Source Type: research

Development and validation of the International Consultation on Incontinence Modular Questionnaire for Male Lower Urinary Tract Symptoms (ICIQ ‐MLUTS) and the ICIQ‐MLUTS Long Form in Chinese population
ObjectiveThe aim of this study was to develop and validate Chinese versions of the International Consultation on Incontinence Modular Questionnaire for Male Lower Urinary Tract Symptoms (ICIQ ‐MLUTS) and ICIQ‐MLUTS Long Form (LF), and to discuss their potential functions.MethodsThe original ICIQ ‐MLUTS and ICIQ‐MLUTS LF were translated into Chinese after obtaining permission from the International Consultation on Incontinence Modular Questionnaire Advisory Board. Between November 2017 and August 2018, the Chinese versions of the ICIQ‐MLUTS and ICIQ‐MLUTS LF were validated by adminis tering them to male patients...
Source: LUTS: Lower Urinary Tract Symptoms - April 3, 2019 Category: Urology & Nephrology Authors: Weina Huang, Qiang Wang, Jiawei Chen, Peng Wu Tags: ORIGINAL ARTICLE Source Type: research

Factors affecting doctor visits of postmenopausal women with urinary incontinence
ConclusionsPatients who suffer from severe UI and whose quality of life is affected more negatively are more likely to visit a doctor. Women who believe that UI is normal are less likely to visit a doctor. Awareness about UI should be increased in order to increase the rate of visiting a doctor for this condition. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - March 27, 2019 Category: Urology & Nephrology Authors: Ismail Biyik, Bilgen Kucuk, Husniye F. Arpaci, Hakan Demirci Tags: ORIGINAL ARTICLE Source Type: research

Pathophysiology of refractory overactive bladder
This article discusses the possible pathophysiologies of refractory OAB. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - March 22, 2019 Category: Urology & Nephrology Authors: Li ‐Chen Chen, Hann‐Chorng Kuo Tags: REVIEW ARTICLE Source Type: research

Exploring stress urinary incontinence outcomes after sling excision for perforation or exposure
ConclusionsMany patients with MUS perforations or exposures will have SUI at initial presentation or develop SUI after removal of the synthetic sling. The decision to perform a concomitant AFPVS or to stage the surgical management of SUI can be individualized. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - March 22, 2019 Category: Urology & Nephrology Authors: Raveen Syan, Benoit Peyronnet, Alice Drain, Ekene Enemchukwu, Dominique R. Malacarne, Nirit Rosenblum, Victor W. Nitti, Benjamin M. Brucker Tags: ORIGINAL ARTICLE Source Type: research

Pathophysiological mechanisms in detrusor underactivity: Novel experimental findings
Underactive bladder (UAB) is a multifactorial symptom complex often related to detrusor underactivity (DU). Although recognized as a common cause of lower urinary tract symptoms and with significant effects on quality of life, UAB/DU is largely underresearched. Herein, we review up ‐to‐date knowledge on the pathophysiological mechanisms of UAB/DU, with an emphasis on the relationship between UAB and bladder outlet obstruction (BOO). Original articles and reviews concerning UAB/DU were identified through a search of the PubMed/Medline and Scopus databases. DU can result fro m several pathological mechanisms, which can b...
Source: LUTS: Lower Urinary Tract Symptoms - March 12, 2019 Category: Urology & Nephrology Authors: Lu ís Vale, Filipa Jesus, Tom Marcelissen, Malte Rieken, Bogdan Geavlete, Mohammad Sajjad Rahnama'i, Frank Martens, Francisco Cruz, Tiago Antunes‐Lopes, on behalf of the EAU Young Academic Urologists Functional Urology Working Group Tags: REVIEW ARTICLE Source Type: research

Feasibility of approximate measurement of bladder volume in male patients using the Lilium α‐200 portable ultrasound bladder scanner
This study examined the accuracy of a new portable ultrasound bladder scanner, the Lilium α‐200 (Lilium Otsuka, Kanagawa, Japan), by evaluating the correlation between bladder volumes periodically measured by the Lilium α‐200 and instilled volume during video‐urodynamic studies (V‐UDS).MethodsUsing the Lilium α‐200, fluid volume was measured prospectively in the bladders of patients with lower urinary tract dysfunction during V‐UDS. This was done both immediately after micturition (for assessment of post‐void residual [PVR] volume) and at 1‐minute intervals during filling cystometry with p...
Source: LUTS: Lower Urinary Tract Symptoms - March 10, 2019 Category: Urology & Nephrology Authors: Jun Kamei, Daiji Watanabe, Yukio Homma, Haruki Kume, Yasuhiko Igawa Tags: ORIGINAL ARTICLE Source Type: research

Evaluation of resistive index of the prostate and bladder sonomorphologic parameters as replacements for urodynamics to predict bladder outlet obstruction in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia
This study investigated whether the resistive index (RI) of prostate and bladder sonomorphologic parameters (total prostate volume [TPV], detrusor wall thickness [DWT], intraprostatic protrusion [IPP]) can be used instead of urodynamic studies (UDS) to predict bladder outlet obstruction (BOO) in benign prostatic hyperplasia (BPH) with lower urinary tract symptoms (LUTS).MethodsMen aged ≥50 years with clinical BPH/LUTS were prospectively enrolled included. Basic evaluations, measurement of sonomorphologic parameters, and UDS were performed in accordance with the International Continence Society's Good Urodynamics ...
Source: LUTS: Lower Urinary Tract Symptoms - February 22, 2019 Category: Urology & Nephrology Authors: Gaurav Garg, Satya Narayan Sankhwar, Apul Goel, Siddharth Pandey, Deepanshu Sharma, Anit Parihar Tags: ORIGINAL ARTICLE Source Type: research

Risk factors for postoperative urinary retention among women who underwent laparoscopic cholecystectomy
ObjectivesThe aim of this study was to investigate the risk factors for postoperative urinary retention (POUR) among female patients by evaluating its occurrence in women who underwent laparoscopic cholecystectomy in Gyeongsang National University Hospital.MethodsThe medical records of female patients who had undergone laparoscopic cholecystectomy for gallbladder stones between March 2014 and February 2018 were reviewed. Information was collected regarding patient age, body mass index (BMI), creatinine, absolute neutrophil count, duration of the operation and anesthesia, the amount of fluid infused, American Society of Ane...
Source: LUTS: Lower Urinary Tract Symptoms - February 3, 2019 Category: Urology & Nephrology Authors: Jae Hwi Choi, Sol Yoon, Sin Woo Lee, Seong Uk Jeh, Jeong Seok Hwa, Jae Seog Hyun, Ky Hyun Chung, Deok Ha Seo, Chunwoo Lee, Sung Chul Kam, See Min Choi Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
LUTS: Lower Urinary Tract Symptoms, Volume 11, Issue 1, Page 1-1, January 2019. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - January 23, 2019 Category: Urology & Nephrology Tags: ISSUE INFORMATION Source Type: research

Feeling of incomplete bladder emptying: A definition with clinical implications
LUTS: Lower Urinary Tract Symptoms, Volume 11, Issue 1, Page 85-85, January 2019. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - January 23, 2019 Category: Urology & Nephrology Authors: Petros Sountoulides, Wilbert F. Mutomba Tags: LETTER TO THE EDITOR Source Type: research

Safety and effectiveness of mirabegron in patients with overactive bladder aged ≥75 years: Analysis of a Japanese post‐marketing study
ObjectivesA 12 ‐week post‐marketing study was conducted to provide real‐world data on Japanese patients with overactive bladder (OAB) initiating treatment with mirabegron. This post‐hoc analysis focused on safety and effectiveness of mirabegron in patients aged ≥75 versus
Source: LUTS: Lower Urinary Tract Symptoms - January 23, 2019 Category: Urology & Nephrology Authors: Masaki Yoshida, Yumiko Nozawa, Daisuke Kato, Hiromi Tabuchi, Kentarou Kuroishi Tags: ORIGINAL ARTICLE Source Type: research

Mirabegron induces relaxant effects via cAMP signaling ‐dependent and ‐independent pathways in detrusor smooth muscle
ConclusionsMirabegron ‐induced relaxation of pig and human detrusor smooth muscle occurs via both a β3‐adrenoceptor/cAMP‐dependent and ‐independent pathway. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - January 10, 2019 Category: Urology & Nephrology Authors: Tomoko Maki, Shunichi Kajioka, Momoe Itsumi, Eljamal Kareman, Ken Lee, Masaki Shiota, Masatoshi Eto Tags: ORIGINAL ARTICLE Source Type: research

Effectiveness and persistence of mirabegron as a first ‐line treatment in patients with overactive bladder in real‐life practice
ObjectivesTo evaluate the effectiveness and persistence of mirabegron as a first ‐line treatment in patients with overactive bladder (OAB) in real‐life practice.MethodsWe retrospectively analyzed patients with OAB who received mirabegron (50  mg) as a first‐line treatment. According to treatment course, patients were divided into three groups, (a) mirabegron only (monotherapy group), (b) mirabegron and anticholinergics (add‐on group), and (c) mirabegron replaced with another treatment (switch group). The patients' symptoms were do cumented with a voiding diary including an urgency scale and a patient percept...
Source: LUTS: Lower Urinary Tract Symptoms - January 8, 2019 Category: Urology & Nephrology Authors: Jung Hyun Shin, Myung ‐Soo Choo Tags: ORIGINAL ARTICLE Source Type: research

Postoperative cystogram findings predict recovery of urinary continence after robot ‐assisted laparoscopic radical prostatectomy
ObjectivesTo assess the association between postoperative cystogram findings and subsequent outcomes on urinary continence after robot ‐assisted laparoscopic radical prostatectomy (RALP).MethodsA retrospective review of 250 consecutive patients who were observed for at least 12  months after RALP. The postoperative cystogram findings examined were: the location of the bladder neck, degree of bladder abnormalities, and presence of outflow of contrast medium into the urethra during the filling phase of cystography. The continence status based on pad usage was recorded. Tho se who required no pad or only a safety pad...
Source: LUTS: Lower Urinary Tract Symptoms - January 4, 2019 Category: Urology & Nephrology Authors: Shinji Fukui, Yoriaki Kagebayashi, Yusuke Iemura, Yoshiaki Matsumura, Shoji Samma Tags: ORIGINAL ARTICLE Source Type: research

Audiovisual stimulus during urodynamics to provoke detrusor overactivity: A randomized trial
ConclusionsAddition of AV intervention during UDE did not increase the finding of detrusor contractions. The relationship between OAB triggers, urge incontinence, and urodynamic findings remains unclear. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - December 18, 2018 Category: Urology & Nephrology Authors: Jonathan Shaw, Nicole Negbenebor, Kyle Wohlrab, Christine Raker, Vivian Sung Tags: ORIGINAL ARTICLE Source Type: research

Higher urge severity score predicts resumption of overactive bladder (OAB) medication following discontinuation of mirabegron treatment in patients with OAB
ConclusionsAmong OAB patients who were successfully treated with mirabegron for ≥3 months, nearly half requested resumption of mirabegron after discontinuation. A higher USS was found to predict retreatment after discontinuation of mirabegron in OAB patients. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - December 18, 2018 Category: Urology & Nephrology Authors: Chung ‐Cheng Wang, Yung‐Hong Jiang, Hann‐Chorng Kuo Tags: ORIGINAL ARTICLE Source Type: research

Use of an occlusive penile clamp during filling cystometry in men with symptoms of stress urinary incontinence
This study evaluated cystometry and pressure flow studies (PFS) in men in whom severe SUI during attempted filling necessitated application of a penile clamp to allow filling to reach cystometric capacity. Men who had undergone prior radical prostatectomy were identified from a database of patients attending for video urodynamic testing between 2012 and 2017. Symptom scores, bladder diary and free flow rate tests were retrieved. Measurements of the subgroup of men for whom a Thomson‐Walker compression clamp was used to enable full urodynamic evaluation were evaluated. 166 patients were identified. In 30 patients (18%), s...
Source: LUTS: Lower Urinary Tract Symptoms - December 18, 2018 Category: Urology & Nephrology Authors: Ala'a Sharaf, Mandy Fader, Margaret Macaulay, Marcus J. Drake Tags: ORIGINAL ARTICLE Source Type: research

Male patients with a higher frequency of nocturnal urinary episodes are more likely to benefit from alpha ‐blocker therapy for bothersome nocturia
ConclusionTamsulosin treatment (0.4  mg, h.s.) for 3 months not only improved voiding and storage symptoms, but also reduced nocturia episodes. Patients with more nocturia episodes may benefit more from alpha‐blocker treatment in terms of reducing the number of nocturia episodes. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - December 12, 2018 Category: Urology & Nephrology Authors: Cheng ‐Ling Lee, Hann‐Chorng Kuo Tags: ORIGINAL ARTICLE Source Type: research

Is obstructive sleep apnea syndrome related to nocturia?
ObjectiveThe aim of this study was to investigate the relationship between obstructive sleep apnea syndrome (OSAS) and lower urinary tract symptoms (LUTS) in patients with benign prostatic hyperplasia (BPH).MethodsThis multicenter study was performed on 122 male patients with dyspnea and/or sleep disorder. Patient characteristics were recorded. All patients underwent full ‐night polysomnography, and the apnea–hypopnea index (AHI) was calculated. LUTS were evaluated using the International Prostate Symptom Score (IPSS) and prostate volume was calculated by transabdominal ultrasonography. Based on the AHI, patients w...
Source: LUTS: Lower Urinary Tract Symptoms - December 12, 2018 Category: Urology & Nephrology Authors: Burak Arslan, Cem T. Gezmis, Bu ğra Çetin, Serkan Gönültas, Ersin Gökmen, Okan Gürkan, Enver Ozdemir Tags: ORIGINAL ARTICLE Source Type: research

Pelvic magnetic resonance imaging parameters predict urinary incontinence after robot ‐assisted radical prostatectomy
ObjectiveUrinary incontinence (UI) is a major prostate cancer (PCa) treatment ‐related morbidity. It has been reported that post‐prostatectomy UI is related to the width of the pelvic floor muscles (PFM) and the length of the urethra. However, the details of these anatomical parameters are unknown. The aim of this study was to investigate whether preoperative pelvic param eters or anatomical parameters of the urethra, as measured by magnetic resonance imaging (MRI), are correlated with UI.MethodsBetween 2010 and 2017, 571 patients with localized PCa underwent robot ‐assisted radical prostatectomy (RARP) at Okayama Un...
Source: LUTS: Lower Urinary Tract Symptoms - December 12, 2018 Category: Urology & Nephrology Authors: Takuya Sadahira, Yosuke Mitsui, Motoo Araki, Yuki Maruyama, Koichiro Wada, Kohei Edamura, Yasuyuki Kobayashi, Masami Watanabe, Toyohiko Watanabe, Yasutomo Nasu Tags: ORIGINAL ARTICLE Source Type: research

Bladder dysfunction does not affect long ‐term success rate of the retropubic suburethral sling procedure in women with stress urinary incontinence
ConclusionsThe overall continence rate was 83.4% and the 10 ‐year continence rate was satisfactory in all bladder function subgroups. Treatment outcomes were the same for women with SUI but different bladder function. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - November 28, 2018 Category: Urology & Nephrology Authors: Hueih Ling Ong, Hann ‐Chorng Kuo Tags: ORIGINAL ARTICLE Source Type: research

A 52 ‐week multicenter randomized controlled study of the efficacy and safety of add‐on dutasteride and imidafenacin to tamsulosin in patients with benign prostatic hyperplasia with remaining overactive bladder symptoms (DIrecT study)
LUTS: Lower Urinary Tract Symptoms, EarlyView. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - October 25, 2018 Category: Urology & Nephrology Authors: Tomonori Yamanishi, Hirotaka Asakura, Narihito Seki, Shoji Tokunaga Source Type: research

Effect of tadalafil add ‐on therapy in patients with persistant storage symptoms refractory to α1‐adrenoceptor antagonist monotherapy for benign prostatic hyperplasia: A randomized pilot trial comparing tadalafil and solifenacin
LUTS: Lower Urinary Tract Symptoms, EarlyView. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 25, 2018 Category: Urology & Nephrology Authors: Shinji Urakami, Kohei Ogawa, Suguru Oka, Kiichi Hagiwara, Shoichi Nagamoto, Haruki Anjiki, Michikata Hayashida, Akihiro Yano, Kazushige Sakaguchi, Kazuhiro Kurosawa, Toshikazu Okaneya Source Type: research

Changes in sensory proteins in the bladder urothelium of patients with chronic kidney disease and end ‐stage renal disease
LUTS: Lower Urinary Tract Symptoms, EarlyView. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 10, 2018 Category: Urology & Nephrology Authors: Sheng ‐Fu Chen , Cheng‐Ling Lee , Hann‐Chorng Kuo Source Type: research

Predictive variables of spontaneous micturition recovery after acute urinary retention in men with benign prostatic enlargement: An observational prospective study
LUTS: Lower Urinary Tract Symptoms, EarlyView. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 5, 2018 Category: Urology & Nephrology Authors: Marco Vella , Alberto Abrate , Angela Costanzo , Francesco D'Amato , Maria L. Tarantino , Alchiede Simonato Source Type: research

Issue information
LUTS: Lower Urinary Tract Symptoms,Volume 10, Issue 3, Page 213-213, September 2018. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 3, 2018 Category: Urology & Nephrology Source Type: research

Does inguinal hernia repair affect uroflowmetric parameters? A prospective controlled clinical trial
LUTS: Lower Urinary Tract Symptoms, EarlyView. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - August 31, 2018 Category: Urology & Nephrology Authors: Yilmaz Unal , Muhammet Fatih Kilinc Source Type: research