Botox rechallenge —An additional tool in the management of an incompletely emptying bladder and inadequate overactive symptom control following sacral neuromodulation
AbstractTwo female patients aged 70 and 72 with video ‐urodynamics‐confirmed detrusor overactivity and detrusor underactivity (DO‐DU) were treated. Patients were refractory to medical therapies and had previously failed intravesical botulinum toxin type A (BoNT‐A) at other centers secondary to urinary retention and difficulty with self‐cathet erization. Placement of an Interstim II device (Medtronic, Minneapolis, Minnesota) for sacral neuromodulation (SNM) as alternative third‐line treatment partially improved overactive bladder (OAB) symptoms while significantly improving voiding symptoms. Postvoid residual (P...
Source: LUTS: Lower Urinary Tract Symptoms - June 16, 2020 Category: Urology & Nephrology Authors: Brennan Timm, Jyotsna Jayarajan, Garson Chan, Damien Bolton Tags: CASE REPORT Source Type: research

Trigonal ‐sparing versus trigonal‐involved Botox injection for treatment of idiopathic overactive bladder: A randomized clinical trial
ConclusionTrigone injections are not superior to trigone ‐sparing injections. On the contrary, the incidence of UTI and voiding difficulty were higher. The concept of reflux induced by trigonal injection has not been proven. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - June 16, 2020 Category: Urology & Nephrology Authors: Ahmed S. El ‐Hefnawy, Mohamed A. Elbaset, Diaa‐Eldin Taha, Bassem S. Wadie, Mahmoud Kenawy, Ahmed A. Shokeir, Mohamed E. Badry Tags: ORIGINAL ARTICLE Source Type: research

Variability of post ‐void residual urine volume and bladder voiding efficiency in patients with underactive bladder
ConclusionsMeasurement of PVR was unreliable because of wide variation in the same individual. The variation of BVE was much smaller than PVR. BVE would be a reliable parameter with good reproducibility for the assessment of emptying function. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - June 11, 2020 Category: Urology & Nephrology Authors: Makoto Yono, Kazuya Ito, Megumi Oyama, Takanori Tanaka, Shin Irie, Yoshihisa Matsukawa, Noritoshi Sekido, Masaki Yoshida, Olivier Till, Osamu Yamaguchi Tags: ORIGINAL ARTICLE Source Type: research

GreenLight HPS laser 120  W vs diode laser 300 W vaporization of the prostate for the treatment of benign prostatic hyperplasia in Japanese patients: A prospective, single‐center, randomized clinical trial
This study aimed to compare the safety and efficacy of laser vaporization with 532  nm GreenLight High Performance System (HPS) laser 120 W (PVP) and 980 nm diode laser 300 W (CVP) for the treatment of benign prostatic hyperplasia (BPH) in a prospective, single‐center, randomized clinical trial.MethodsA total of 153 consecutive patients with symptomatic BPH were included; 79 patients were treated with PVP and 74 with CVP. Patients were assessed preoperatively and at 3, 6, and 12  months postoperatively using the International Prostate Symptom Score, quality of life index, peak urinary f...
Source: LUTS: Lower Urinary Tract Symptoms - June 9, 2020 Category: Urology & Nephrology Authors: Takeshi Kobayashi, Narihito Seki, Yoo H. Song, Takashi Dejima Tags: ORIGINAL ARTICLE Source Type: research

Intralesional steroid injection combined with bladder neck incision is efficacious in the treatment of recurrent bladder neck contracture
ConclusionsBNI combined with injection of intralesional steroids is a simple, cost ‐effective intervention which requires no specialist equipment/skills outside the realm of a general urologist. It is safe and has an excellent success rate. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - June 8, 2020 Category: Urology & Nephrology Authors: Jordan A. Mann, Joshua Silverman, Andre Westenberg Tags: ORIGINAL ARTICLE Source Type: research

Female bladder neck dysfunction —Avideo‐urodynamic diagnosis among women with voiding dysfunction
AbstractObjectiveTo investigate bladder neck dysfunction (BND) in women with voiding dysfunction by video ‐urodynamic study (VUDS) and to examine the therapeutic results of different BND subtypes.Materials and MethodsWe retrospectively reviewed consecutive women who had undergone VUDS for investigation of voiding dysfunction at our institution. The diagnosis of BND was made based on a nonfunneling bladder neck with or without high voiding detrusor pressure. Patients diagnosed as BND were retrieved, and the urodynamic parameters were compared with patients with dysfunctional voiding (DV) and other bladder outlet obstructi...
Source: LUTS: Lower Urinary Tract Symptoms - June 8, 2020 Category: Urology & Nephrology Authors: Hueih Ling Ong, Cheng ‐Ling Lee, Hann‐Chorng Kuo Tags: ORIGINAL ARTICLE Source Type: research

Overactive bladder and sleep disturbance have a significant effect on indoor falls: Results from the community health survey in Japan
ConclusionsThe effect of OAB symptoms and sleep disturbance on indoor fall events was significant. The causal relationship between OAB and falls needs further study. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - June 4, 2020 Category: Urology & Nephrology Authors: Sakae Konishi, Shingo Hatakeyama, Atsushi Imai, Mika Kumagai, Kazutaka Okita, Kyo Togashi, Tomoko Hamaya, Itsuto Hamano, Teppei Okamoto, Hiromichi Iwamura, Hayato Yamamoto, Takahiro Yoneyama, Yasuhiro Hashimoto, Chikara Ohyama Tags: ORIGINAL ARTICLE Source Type: research

Pooled analysis of the efficacy and safety of intraoperative dexmedetomidine on postoperative catheter ‐related bladder discomfort
This study was carried out using the preferred reporting items for systematic reviews and pooled analysis. We used RevMan version 5.3.0. to analyze the data.ResultsSeven RCTs involving 607 patients were brought into in the analysis. The incidence of CRBD and the incidence of moderate to severe CRBD were assessed at 0  hours, 0.5 or 1 hour, 2 or 3 hours, 6 hours, and 12 or 24 hours postoperatively. The analysis proved that both the incidence of CRBD (P 
Source: LUTS: Lower Urinary Tract Symptoms - June 4, 2020 Category: Urology & Nephrology Authors: Hongbin Shi, Huaping Zhang, Weizhong Pan, Youyi Lu, Yong Zhang, Linjing Chen, Chunxiao Wei, Yuanshan Cui Tags: ORIGINAL ARTICLE Source Type: research

Standardization for reliable uroflowmetry testing in adults
This study has been registered in the UMIN Clinical Trials Registry (UMIN000035446).ResultsThe benign prostatic obstruction group and the healthy volunteer group presented no difference in respect of uroflowmetry test reliability (P =  .459). Uroflowmetry results were reliable in 58 (78.4%) subjects in the prehydrated group and was reliable in 30 (40.5%) subjects in the non‐prehydrated group. The difference was statistically significant (P
Source: LUTS: Lower Urinary Tract Symptoms - May 26, 2020 Category: Urology & Nephrology Authors: Erman Ceyhan, Mehmet K. Asutay Tags: ORIGINAL ARTICLE Source Type: research

Serum creatinine levels in cases of posterior urethral valve: 29  years experience of a pediatric urology reference center
ConclusionsIn patients with posterior urethral valves, nadir creatinine, especially higher than 1  mg/dL, should be considered as high risk for end‐stage renal disease. Therefore, clinicians should improve awareness about early detection and treatment of posterior urethral valves, and these patients should be monitored as early as possible for the risk of chronic kidney disease. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - May 19, 2020 Category: Urology & Nephrology Authors: Hasan Demirkan, Cumhur Ye şildal Tags: ORIGINAL ARTICLE Source Type: research

Does tamsulosin or mirabegron improve ureteral stent ‐related symptoms? A prospective placebo‐controlled study
AbstractObjectiveThe main objective of this study was to evaluate the efficacy of tamsulosin or mirabegron on ureteral stent ‐related symptoms.Patients and methodsThis was a prospective, randomized, controlled, and single ‐blinded study. In total, 180 patients who had undergone ureterolithotripsy and ureteral stent insertion were included. Patients were randomly divided into three groups as follows: Group 1 was the control group taking placebo; group 2 was administered tamsulosin (0.4 mg) once a day; and group 3 received mirabegron (50 mg) once a day. The Turkish version of the ureteral stent symptom ques...
Source: LUTS: Lower Urinary Tract Symptoms - May 14, 2020 Category: Urology & Nephrology Authors: Abdulmecit Yavuz, Muhammet F. Kilinc, Mustafa Aydin, Yilmaz Ofluoglu, G öksel Bayar Tags: ORIGINAL ARTICLE Source Type: research

Sodium plays an important role in the absorption of intravesical fluid
ConclusionsThe presence of sodium is important for the absorption of intravesical fluid through aquaporin ‐2 in the urinary bladders of rats. Claudin‐3 and ‐6 may be associated with the transport of sodium through the bladder urothelium. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - May 14, 2020 Category: Urology & Nephrology Authors: Yosuke Morizawa, Kazumasa Torimoto, Shunta Hori, Daisuke Gotoh, Yasushi Nakai, Makito Miyake, Nobumichi Tanaka, Akihide Hirayama, Kiyohide Fujimoto Tags: ORIGINAL ARTICLE Source Type: research

EP2 and EP3 receptors as therapeutic targets for underactive bladder/detrusor underactivity due to diabetic cystopathy in a type 1 diabetic rat model
In this study, we investigated whether EP2 and EP3 receptors are promising targets of pharmacological management of UAB/DU due to DC.MethodsWe used streptozotocin (STZ) ‐induced diabetic Sprague‐Dawley rats with postvoid residual urine (PVR) greater than 0.1 mL. Sixteen weeks after induction of diabetes, we performed awake single cystometry after oral administration of the vehicle, an α‐blocker (tamsulosin [TAM], 0.1 and 0.3 mg/kg), a cholinesterase inhi bitor (distigmine [DIS], 0.3 and 1.0 mg/kg), or an EP2/3 dual agonist (ONO‐8055, 0.01 and 0.03 mg/kg). We compared cystometric pa...
Source: LUTS: Lower Urinary Tract Symptoms - May 14, 2020 Category: Urology & Nephrology Authors: Noritoshi Sekido, Takeya Otsuki, Jun Kida, Hiroko Mashimo, Daisuke Wakamatsu, Hiroki Okada, Hidekazu Matsuya Tags: ORIGINAL ARTICLE Source Type: research

Correlation between lumbar skeletal muscle size and urinary incontinence after radical prostatectomy
AbstractObjectivesUrinary incontinence is a major concern after radical prostatectomy because it can decrease quality of life. The aim of the present study was to explore the effect of preoperative skeletal muscle on urinary quality of life after robot ‐assisted radical prostatectomy.MethodsA total of 762 patients underwent robot ‐assisted radical prostatectomy. Longitudinal health‐related quality of life was evaluated using the Expanded Prostate Cancer Index Composite instrument. The skeletal muscle area at the level of the third lumbar vertebra was assessed preoperatively by computed tomography and was standardized...
Source: LUTS: Lower Urinary Tract Symptoms - May 6, 2020 Category: Urology & Nephrology Authors: Yosuke Mitsui, Takuya Sadahira, Toyohiko Watanabe, Motoo Araki, Yuki Maruyama, Ryota Sato, Acosta Gonzalez Herik Rodrigo, Koichiro Wada, Masami Watanabe, Michael B. Chancellor, Yasutomo Nasu Tags: ORIGINAL ARTICLE Source Type: research

Lower urinary tract function improves after laparoscopic sacrocolpopexy for elderly patients with pelvic organ prolapse
We examined bladder functions by evaluating bladder capacity, detrusor pressure at maximum flow (PdetQmax), maximum flow rate (Qmax), normal desire to void, strong desire to void, voided volume, and postvoid residual volume (PVR). Statistical analysis was performed using Wilcoxon signed rank test. Values ofP 
Source: LUTS: Lower Urinary Tract Symptoms - April 29, 2020 Category: Urology & Nephrology Authors: Mio Togo, Takeya Kitta, Yukiko Kanno, Mifuka Ouchi, Shino Tokiwa, Tingwen Huang, Shingo Moriyama, Jimmy Nomura, Kimihiko Moriya, Nobuo Shinohara Tags: ORIGINAL ARTICLE Source Type: research

How do urinary incontinence types affect sexual function and quality of life for Turkish women?
ConclusionThe sexual function of women with MUI was affected more adversely than the other UI subtypes. There was no statistically significant difference between the UI subtypes according to IIQ ‐7 scores, but when we examined the scores, MUI and UUI were found to have more negative effects on QoL. Clinicians and continence nurses should make routine evaluations of sexual function and QoL for women according to UI subtypes. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - April 28, 2020 Category: Urology & Nephrology Authors: Dilek Bilgic, Nezihe Kizilkaya Beji Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
LUTS: Lower Urinary Tract Symptoms, Volume 12, Issue 2, Page 107-107, May 2020. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - April 27, 2020 Category: Urology & Nephrology Tags: ISSUE INFORMATION Source Type: research

Contemporary use of prescription medications for neurogenic lower urinary tract dysfunction
ConclusionsThis is the first study to analyze the use of medical therapy for NLUTD in a large outpatient setting. Further prospective evaluation of patient satisfaction and efficacy of both single anticholinergic medication and dual therapy is needed. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - April 24, 2020 Category: Urology & Nephrology Authors: Aidan Kennedy, Alana Christie, Rena D. Malik, Philippe E. Zimmern Tags: ORIGINAL ARTICLE Source Type: research

Longitudinal changes in patient ‐reported outcomes after artificial urinary sphincter implantation
AbstractObjectiveTo evaluate the time course of lower urinary tract symptoms (LUTS) after artificial urinary sphincter (AUS) implantation based on individual longitudinal changes of patient ‐reported outcomes.MethodsThis retrospective study included 66 male patients with severe urinary incontinence who were treated with primary AUS implantation between 2009 and 2019. International Consultation on Incontinence Questionnaire ‐Short Form (ICIQ‐SF) and International Prostate Symptom Score (IPSS) questionnaires were used to evaluate continence status and LUTS preoperatively, 1, 3, and 12 months after activation, an...
Source: LUTS: Lower Urinary Tract Symptoms - April 13, 2020 Category: Urology & Nephrology Authors: Minato Yokoyama, Hitoshi Masuda, Masaya Ito, Yuma Waseda, Shingo Moriyama, Masahiro Toide, Yusuke Uchida, Sho Uehara, Toshiki Kijima, Soichiro Yoshida, Junichiro Ishioka, Yoh Matsuoka, Kazutaka Saito, Yasuhisa Fujii Tags: ORIGINAL ARTICLE Source Type: research

Our experiences in bipolar radiofrequency thermotherapy system as an alternative treatment in LUTS
In this study we found there was 48.8% increase in Qmax, 72.1% decrease in IPSS, 70.8% decrease in the QoL score, 51.1% decrease in PVR of 80 patients who underwent bipolar radiofrequency prostate ablation. The bipolar radiofrequency prostate thermotherapy system can be safely applied as an outpatient treatment in high‐risk cases or for those who are anxious about surgical interventions. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - March 30, 2020 Category: Urology & Nephrology Authors: Özbay Engin, Salar Remzi, Öncel Halil Ferat Tags: ORIGINAL ARTICLE Source Type: research

The prevalence of urinary incontinence in men and women aged 40  years or over in China, Taiwan and South Korea: A cross‐sectional, prevalence‐based study
ConclusionUI was associated with substantial problems, including an adverse impact on HRQoL. Medication failed to satisfy many individuals with UI. Efforts to educate the public and physicians about the impact of UI could improve diagnosis and treatment rates. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - March 24, 2020 Category: Urology & Nephrology Authors: Budiwan Sumarsono, Jar Jar Jong, Jian ‐Ye Wang, Limin Liao, Kyu‐Sung Lee, Tag Keun Yoo, Shih‐Ping Liu, Yao‐Chi Chuang Tags: ORIGINAL ARTICLE Source Type: research

The effect of transobturator tape operation on sexual functions of a patient with stress urinary incontinence and patient's spouse
AbstractPurposeThis prospective study aimed to investigate the effects of transobturator tape (TOT) procedure on patients with stress urinary incontinence (SUI) and their spouses' sexual function.Material and methodsA total of 157 patients with SUI who underwent TOT operation between January 2017 and May 2019 and their spouses were included. All patients enrolled filled out the Incontinence Impact Questionnaire (IIQ ‐7), the Urogenital Distress Inventory (UDI‐6), the Female Sexual Function Index (FSFI), and patients' spouses filled out International Index of Erectile Function (IIEF‐5) before surgery and 6 months afte...
Source: LUTS: Lower Urinary Tract Symptoms - March 13, 2020 Category: Urology & Nephrology Authors: S üleyman Cemil Oğlak, Mehmet Obut Tags: ORIGINAL ARTICLE Source Type: research

Lower urinary tract symptoms and related factors in female university students
ConclusionsLower urinary tract complaints are a common problem. We believe that routine medical screening should be performed for female university students whose living conditions change when they start university; besides, we suggest that well ‐attended and repeatable training programs for healthy living behaviors, urinary habits, and hygiene should be organized for university students. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - February 28, 2020 Category: Urology & Nephrology Authors: Sebahat G ücük, Ülkü M. Ural, Mehmet Kayhan, Adnan Gücük Tags: ORIGINAL ARTICLE Source Type: research

Current management of refractory overactive bladder
AbstractOveractive bladder (OAB) is a common condition affecting one ‐sixth to one‐fifth of the global population. The treatment of refractory OAB remains a challenge for urologists. Current treatment options include the use of combination therapy with antimuscarinic agents and beta‐3 adrenoceptor agonists, and treating underlying curable disorders. Intravesica l botulinum toxin type A (BoNT‐A) injection, percutaneous tibial nerve stimulation, and sacral nerve stimulation are third‐line management therapies suggested by the American Urological Association/Society of Urodynamics, Female Pelvic Medicine& Urogen...
Source: LUTS: Lower Urinary Tract Symptoms - February 20, 2020 Category: Urology & Nephrology Authors: Li ‐Chen Chen, Hann‐Chorng Kuo Tags: REVIEW ARTICLE Source Type: research

Therapeutic effects of Choreito, a traditional Japanese (Kampo) medicine, on detrusor overactivity induced by acetic acid in rats
This study aimed to identify the effects and therapeutic mechanism of CRT on the improvement of detrusor overactivity (DO) using an experimental rat model. Forty ‐five female Sprague‐Dawley rats were equally divided into three groups: intravesical saline instillation with normal food (normal group), intravesical acetic acid (AA) instillation with normal food (AA group), and intravesical AA instillation with CRT (AA with CRT group). To induce a decrease i n bladder capacity, instillation of 0.2% AA was used based on prior studies. Cystometric investigation was employed to clarify the effects of AA and CRT. Microcirculat...
Source: LUTS: Lower Urinary Tract Symptoms - February 4, 2020 Category: Urology & Nephrology Authors: Manabu Ueno, Tomonori Minagawa, Tetsuichi Saito, Tetsuya Imamura, Takashi Nagai, Teruyuki Ogawa, Osamu Ishizuka Tags: ORIGINAL ARTICLE Source Type: research

Quality of life and sexuality after bilateral sacrospinous fixation with vaginal hysterectomy for treatment of primary pelvic organ prolapse
AbstractObjectiveTo investigate the quality of life (QoL) and sexuality in women affected by pelvic organ prolapse (POP) and treated by bilateral sacrospinous ligament fixation (SSLF) with vaginal hysterectomy.MethodsThis is a prospective observational study carried out at Isparta City Hospital from July 2017 to December 2018. A total of 26 sexually active women with symptomatic uterine prolapse POP ‐Q (Pelvic Organ Prolapse Quantification) stage II or higher requiring surgery were included in the study. Short Form Health Survey (SF‐36) was used preoperatively and at 6 months to examine the impacts of vaginal re...
Source: LUTS: Lower Urinary Tract Symptoms - January 31, 2020 Category: Urology & Nephrology Authors: Yakup Yalcin, Melike Demir Caltekin, Serenat Eris Yalcin Tags: ORIGINAL ARTICLE Source Type: research

Flow resistive forces index (QRF): Development and clinical applicability assessment of a novel measure of bladder outlet resistance, aiming to enhance the diagnostic performance of uroflowmetry
AbstractBackgroundCurrently, the diagnostic ability of uroflowmetry, the most widely used urodynamic test available for initial assessment of patients with lower urinary tract symptoms (LUTS), is considered limited by its inability to accurately discriminate between the underlying mechanisms of this condition. To improve the diagnostic accuracy of uroflow, we developed a mathematical formula that calculates the flow resistive forces index (QRF), a novel measure of bladder outflow/urethral resistance, and assessed its clinical applicability compared to the maximum flow rate (Qmax).Materials and MethodsA cross ‐sectional o...
Source: LUTS: Lower Urinary Tract Symptoms - January 30, 2020 Category: Urology & Nephrology Authors: Evangelos Spyropoulos, Ioannis Galanakis, Dimitrios Deligiannis, Aikaterini Spyropoulou, Dimitrios Kotsiris, Aggelos Panagopoulos, Stamatios Mavrikos Tags: ORIGINAL ARTICLE Source Type: research

Self ‐perception of symptoms, medical help seeking, and self‐help strategies of women with interstitial cystitis/painful bladder syndrome
This study aims to investigate the self ‐perception of symptoms, medical help seeking, and self‐help strategies of women with interstitial cystitis (IC).MethodsA mixed method of qualitative and quantitative approaches was employed. The qualitative approach used in ‐depth interviews about the subjective experience of symptoms, medical help seeking, and self‐help strategies for their IC. The quantitative inquiry was conducted by a yes or no response to the question “Did self‐perceived severe symptoms of IC interfere with your daily life?” A loglinear model was applied to investigate the associations bet...
Source: LUTS: Lower Urinary Tract Symptoms - January 22, 2020 Category: Urology & Nephrology Authors: Hui ‐Chun Chen, Chieh‐Yu Liu, Chun‐Hou Liao, Lee‐Ing Tsao Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
LUTS: Lower Urinary Tract Symptoms, Volume 12, Issue 1, Page 1-1, January 2020. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - January 10, 2020 Category: Urology & Nephrology Tags: ISSUE INFORMATION Source Type: research

How long does the effect of botulinum toxin in neurogenic patients last? An analysis of the subset of “good responders”
ConclusionThe results of our study indicate that the application of BoNT ‐A seems to be an effective and durable treatment in a large number of neurogenic patients after more than 10 years of follow‐up. However, botulinum toxin tolerance occurred in approximately 25% of patients. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - December 19, 2019 Category: Urology & Nephrology Authors: In ès Dominique, Benjamin Tremblais, Kathleen Charvier, Maria C. S. Nogueira, Philippe Paparel, Nicolas Morel Journel, Alain Ruffion Tags: ORIGINAL ARTICLE Source Type: research

Predictive factors for persistence of preoperative overactive bladder symptoms after transvaginal mesh surgery in women with pelvic organ prolapse
ConclusionTransvaginal mesh surgery eliminates overactive bladder symptoms in about two ‐thirds of pelvic organ prolapse patients. The preoperative International Prostate Symptom Score storage subscore was the most useful predictive factor for the persistence of preoperative overactive bladder symptoms after surgery. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - December 14, 2019 Category: Urology & Nephrology Authors: Atsushi Otsuka, Kyohei Watanabe, Yuto Matsushita, Hiromitsu Watanabe, Keita Tamura, Daisuke Motoyama, Toshiki Ito, Takayuki Sugiyama, Hideaki Miyake Tags: ORIGINAL ARTICLE Source Type: research

Increased bladder sensation without detrusor overactivity revisited: Use of a five ‐grade sensory measure
AbstractAimsIncreased bladder sensation (IBS) without detrusor overactivity (DO) is still a matter of debate, regarding its clinical relevance, urodynamic nature, underlying pathology, and management. Among these, we present our data focusing on the urodynamic nature of IBS without DO, by applying our five ‐grade sensory measure during urodynamics.MethodsWe enrolled 400 individuals who visited our laboratory for screening of lower urinary tract function, mostly with neurogenic etiologies. They included 74 control, 87 DO (irrespective of IBS), and 239 IBS (defined as first sensation
Source: LUTS: Lower Urinary Tract Symptoms - December 13, 2019 Category: Urology & Nephrology Authors: Fuyuki Tateno, Ryuji Sakakibara, Yosuke Aiba, Osamu Takahashi, Ayami Shimizu, Takeshi Oki Tags: ORIGINAL ARTICLE Source Type: research

Transurethral resection in women with symptomatic keratinizing squamous metaplasia of urinary bladder: A retrospective study of 92 cases
AbstractObjectivesTo investigate the efficacy of transurethral resection (TUR) on relieving urinary symptoms in patients with keratinizing squamous metaplasia (KSM) of the urinary bladder.MethodsData were analyzed from a retrospective study of patients receiving transurethral bipolar plasma resection (bi ‐TUR) treatment for symptomatic KSM. Urinary symptoms were assessed by the International Prostate Symptom Score (IPSS) and a numeric rating scale pain score. Efficacy was assessed using the IPSS to determine changes from baseline in lower urinary tract symptoms (LUTS). Self‐reported quality of l ife (QoL) was assessed ...
Source: LUTS: Lower Urinary Tract Symptoms - November 24, 2019 Category: Urology & Nephrology Authors: Huan Wang, Tie Chong, Xiu ‐Ying Tang, Wen‐Bo Zheng Tags: ORIGINAL ARTICLE Source Type: research

Effects of combined treatment with fesoterodine and mirabegron in a pelvic congestion rat model: Results from in vitro and in vivo functional studies
ConclusionsThe combination of 5 ‐hydroxymethyl tolterodine with mirabegron suggests the potential of synergistic effects in a rat pelvic congestion model. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - November 22, 2019 Category: Urology & Nephrology Authors: Kimio Sugaya, Hidetomi Yamagami, Saori Nishijima, Katsumi Kadekawa, Masanori Hizue, Yoshihiko Ito, Shizuo Yamada Tags: ORIGINAL ARTICLE Source Type: research

Phase I study of KRP ‐116D, a 50% w/w dimethyl sulfoxide aqueous solution, on the systemic absorption from bladder by intravesical instillation in healthy Japanese subjects
AbstractObjectiveThis was a single ‐institution, single‐dose, single‐arm phase 1 study in healthy adult males to evaluate the safety and absorption of dimethyl sulfoxide (DMSO) from the bladder into the body when KRP‐116D (a 50% w/w DMSO solution) was intravesically administered and allowed to remain in the bladder for 15 m inutes.MethodsSix healthy adult males were enrolled in this study. KRP ‐116D (50 mL) was instilled directly into the bladder via a catheter where it was allowed to remain for 15 minutes under lidocaine anesthesia in accordance with the usage of RIMSO‐50 (50% w/w DMSO sol...
Source: LUTS: Lower Urinary Tract Symptoms - November 6, 2019 Category: Urology & Nephrology Authors: Hideyo Shimada, Makoto Yono, Yuya Hojo, Yuka Hamamura, Atsushi Ootsuki Tags: ORIGINAL ARTICLE Source Type: research

Surgical results in women with detrusor underactivity and stress urinary incontinence undergoing suburethral sling procedure —Predictive factors for successful outcome
ConclusionsFor women with SUI and coexistent DU who underwent suburethral sling procedure, low IIQ ‐7 (≤6) scores and higher Qmax (≥6 mL/s) are predictors for improvement of surgical outcome. A Qmax of
Source: LUTS: Lower Urinary Tract Symptoms - November 5, 2019 Category: Urology & Nephrology Authors: Ching ‐Jung Chen, Soon‐Chin Yeoh, Hsin‐Tzu Yeh, Sheng‐Mou Hsiao, Hann‐Chorng Kuo Tags: ORIGINAL ARTICLE Source Type: research

Long ‐standing nonulcerative bladder pain syndrome: Impact of Thiele massage on bladder and sexual domains
AbstractPurpose: To assess the efficacy of Thiele massage (TM) as monotherapy for nonulcerative interstitial cystitis/bladder pain syndrome (IC/BPS).Methods: A prospective evaluation of 40 women with IC/BPS who underwent TM was conducted. TM was initially administrated by a physiotherapist and then self ‐administrated at home twice weekly for 16 weeks. Patients were assessed every 4 weeks on an outpatient basis. Assessment tools included 3‐day voiding diaries, the Likert visual analog scale (VAS) for pain, and the Interstitial Cystitis Symptom Index (ICSI) and the Interstitial Cystitis Prob lem Index (ICP...
Source: LUTS: Lower Urinary Tract Symptoms - October 24, 2019 Category: Urology & Nephrology Authors: Ahmed S. El ‐Hefnawy, Hanan Mohamed Mohamed Soliman, Shaimaa Omar Mohamed Abd‐Elbary, Wafaa Ismail Shereif Tags: ORIGINAL ARTICLE Source Type: research

Relationship between frailty and lower urinary tract symptoms among community ‐dwelling adults
ConclusionsIndividuals with LUTS are potentially frailer than those without LUTS. Although the influence of frailty on LUTS is different depending on the measurement tool, attention for frailty is necessary for subjects with LUTS. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - October 23, 2019 Category: Urology & Nephrology Authors: Osamu Soma, Shingo Hatakeyama, Atsushi Imai, Teppei Matsumoto, Itsuto Hamano, Naoki Fujita, Hiromichi Iwamura, Teppei Okamoto, Hayato Yamamoto, Yuki Tobisawa, Tohru Yoneyama, Takahiro Yoneyama, Yasuhiro Hashimoto, Shigeyuki Nakaji, Chikara O Tags: ORIGINAL ARTICLE Source Type: research

Effects of low ‐frequency intravaginal electrical stimulation on female urinary incontinence, quality of life, and urinary symptoms: A pilot study
This study investigated the effects of a low ‐frequency home‐based incontinence therapy device on quality of life (QoL) and urinary symptoms in women with urinary incontinence. From May 2017 to February 2018, 34 patients, aged ≥ 20 years, with involuntary urine leakage>2 times/week, were recruited to this study. Patients with severe pelvic organ prolapse, pregnancy, virgin status, and psychological problems were excluded. The incontinence home ‐care device treatments were administered in 12‐minute sessions, twice daily for 8 weeks. Simultaneously, hyperthermic conditions of 35°C to 40...
Source: LUTS: Lower Urinary Tract Symptoms - October 9, 2019 Category: Urology & Nephrology Authors: Sangrak Bae, Kyu Won Lee, Hyun Cheol Jeong, Bong Hee Park, Woong Jin Bae, Yong Seok Lee, Chang Hee Han, Sung Hak Kang, Sae Woong Kim Tags: ORIGINAL ARTICLE Source Type: research

A matched ‐pair analysis of patients with medium‐sized prostates (50 cc) treated for male LUTS with HoLEP or TURP
AbstractObjectivesTo evaluate perioperative parameters, early functional outcomes, and the safety profile in a matched ‐pair analysis of lower urinary tract symptom (LUTS) patients treated with holmium laser enucleation of the prostate (HoLEP) or transurethral resection of the prostate (TURP).MethodsWe conducted a retrospective, matched ‐pair analysis of 2011 men treated for LUTS in our institution from 2013 to 2017. In the final analysis, 197 patients (HoLEP n = 97; TURP n = 98) were matched for prostate size (50 cc), age, and body mass index, and both cohorts were compared for demographic parameters, clinical ...
Source: LUTS: Lower Urinary Tract Symptoms - October 1, 2019 Category: Urology & Nephrology Authors: Giuseppe Magistro, Thilo Westhofen, Christian G. Stief, Philipp Weinhold Tags: ORIGINAL ARTICLE Source Type: research

Cardiovascular safety of antimuscarinic add ‐on therapy in patients with overactive bladder who had a suboptimal response to mirabegron monotherapy: A post hoc analysis from the Japanese MILAI II study
ConclusionA favorable CV safety profile was observed following long ‐term combination treatment with mirabegron and an antimuscarinic in patients with OAB symptoms. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 30, 2019 Category: Urology & Nephrology Authors: Takao Katoh, Yasuhiko Igawa, Osamu Yamaguchi, Daisuke Kato, Takuya Hamada, Kentaro Kuroishi Tags: ORIGINAL ARTICLE Source Type: research

Association between the neutrophil ‐to‐lymphocyte ratio and intravesical prostatic protrusion in men with benign prostatic hyperplasia
AbstractObjectiveTo analyze the association between neutrophil ‐to‐lymphocyte ratio (NLR) and intravesical prostatic protrusion (IPP) in men with benign prostatic hyperplasia.MethodsTwo hundred and fifty men aged>50  years who presented with lower urinary tract symptoms at our institution between 2014 and 2018 were analyzed. Pearson's method was used for analysis of the correlation between NLR and IPP. Multivariate logistic regression analysis was used to identify predictors of IPP. Further analysis according to total prostate volume (TPV) was performed.ResultsThe NLR correlated positively with IPP (Pearson's r = 0.459,P
Source: LUTS: Lower Urinary Tract Symptoms - September 15, 2019 Category: Urology & Nephrology Authors: Mun Su Chung, Yun Jung Yang, Seung Hwan Lee, Byung Il Yoon Tags: ORIGINAL ARTICLE Source Type: research

Issue Information
LUTS: Lower Urinary Tract Symptoms, Volume 11, Issue 4, Page 175-175, September 2019. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 11, 2019 Category: Urology & Nephrology Tags: ISSUE INFORMATION Source Type: research

Hyperlipidemia as a risk factor for discontinuation of prescribed antimuscarinics among geriatric overactive bladder patients
LUTS: Lower Urinary Tract Symptoms, Volume 11, Issue 4, Page 255-256, September 2019. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - September 11, 2019 Category: Urology & Nephrology Authors: Yu ‐Chen Chen, Hao‐Wei Chen, Yung‐Shun Juan Tags: LETTER TO THE EDITOR Source Type: research

High incidence of lower urinary tract dysfunction in women with recurrent urinary tract infections
AbstractThe aim of this study was to evaluate lower urinary tract dysfunction (LUTD) in women with recurrent urinary tract infections (UTIs). One hundred consecutive female patients with recurrent UTIs who underwent videourodynamic study (VUDS) were included. Another 25 women free from recurrent UTIs served as controls. All the underlying diseases, urine analysis and culture results, VUDS findings, and treatment outcomes of voiding dysfunction were carefully reviewed and analyzed. The mean age of the recurrent UTIs patients was 64.0 ± 16.0 years. Storage and voiding dysfunctions were found in 90 (90%) patient...
Source: LUTS: Lower Urinary Tract Symptoms - August 29, 2019 Category: Urology & Nephrology Authors: Ping ‐Jui Lee, Hann‐Chorng Kuo Tags: ORIGINAL ARTICLE Source Type: research

Association of midline prostatic cysts and lower urinary tract symptoms: A case ‐control analysis of 606 transrectal ultrasound findings
ConclusionsThe presence of MPCs is not an independent factor for moderate to severe LUTS, and the size of the MPCs does not have any correlation to LUTS scores either. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - August 29, 2019 Category: Urology & Nephrology Authors: Bumsoo Park, Sung ‐Ho Ju, Seol Ho Choo Tags: ORIGINAL ARTICLE Source Type: research

Influence of alpha ‐adrenoceptor antagonists therapy on stool form in patients with lower urinary tract symptoms suggestive of benign prostatic hyperplasia
ConclusionsThis study suggests that silodosin was associated with increased digestive symptoms such as diarrhea and loose stools. Therefore, oral drugs for BPH need to be selected by taking into consideration the possibility of digestive symptoms including both the state and type of stools. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - August 29, 2019 Category: Urology & Nephrology Authors: Seiji Matsumoto, Sachiko Kasamo, Kazumi Hashizume Tags: ORIGINAL ARTICLE Source Type: research

Cognitive burden and polypharmacy in elderly Japanese patients treated with anticholinergics for an overactive bladder
This study aimed to investigate the cognitive burden and polypharmacy in elderly patients treated with anticholinergics for an overactive bladder. We conducted a retrospective study of patients with an overactive bladder receiving treatment at two hospitals in Japan (Nara Medical University Hospital and Saiseikai Nara Hospital). Prescription data were collected from the medical records of the patients registered between January 2013 and April 2014. The Anticholinergic Cognitive Burden Scale was used to estimate the severity of the anticholinergic effects on the cognition of each patient. We collected the prescription data ...
Source: LUTS: Lower Urinary Tract Symptoms - August 28, 2019 Category: Urology & Nephrology Authors: Takako Shiota, Kazumasa Torimoto, Masahiro Okuda, Ryo Iwata, Hiromi Kumamoto, Makito Miyake, Akihide Hirayama, Nobumichi Tanaka, Kiyohide Fujimoto Tags: ORIGINAL ARTICLE Source Type: research

Evaluation of the effect of a new method on the pelvic organ prolapse symptoms
ConclusionThis new method of postural or positional inversion leads to a greater improvement in symptoms of pelvic organ prolapse. (Source: LUTS: Lower Urinary Tract Symptoms)
Source: LUTS: Lower Urinary Tract Symptoms - August 26, 2019 Category: Urology & Nephrology Authors: Zahra Gorji, Abbas A. Pourmomeny, Maryam Hajhashemy Tags: ORIGINAL ARTICLE Source Type: research

Predictive factors for recovery of voiding function after transurethral prostate surgery in men with small prostate volume and very low detrusor contractility
This study aims to investigate effectiveness and predictors of voiding function recovery after prostate surgery in patients with DU.MethodsMale patients with DU and small total prostate volume (TPV,
Source: LUTS: Lower Urinary Tract Symptoms - August 20, 2019 Category: Urology & Nephrology Authors: Shu ‐Yu Wu, Hann‐Chorng Kuo Tags: ORIGINAL ARTICLE Source Type: research