Mechanisms of YAP1-mediated trophoblast ferroptosis in recurrent pregnancy loss

ConclusionDownregulation of YAP1 induces ferroptosis, thereby damaging the trophoblast invasion processes, which also disturbs the communication at the maternal-fetal interface. Our study identified YAP1 as a potential key molecule in the pathogenesis of RPL.
Source: Journal of Assisted Reproduction and Genetics - Category: Reproduction Medicine Source Type: research