Spatial transcriptomics reveals a low extent of transcriptionally active hepatitis B virus integration in patients with HBsAg loss
Conclusion
Transcriptionally active HBV integration occurred in chronically HBV-infected patients at different phases, including in patients with HBsAg loss. Antiviral treatment was associated with a decreased number and extent of transcriptionally active viral integrations, implying that early treatment intervention may further reduce the number of viral integration events.
Source: Gut - Category: Gastroenterology Authors: Yu, X., Gong, Q., Yu, D., Chen, Y., Jing, Y., Zoulim, F., Zhang, X. Tags: Open access, Gut Hepatology Source Type: research
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