An Immunocompetent Mongolian Gerbil Model for Hepatitis E Virus Genotype 1 Infection

Hepatitis E virus (HEV), primarily genotype 1 (HEV-1), causes approximately 20.1 million infections, 44000 deaths, and 3000 stillbirths annually. Current evidence indicates that HEV-1 is only transmitted in humans. Here, we evaluated whether Mongolian gerbils can serve as animal models for HEV-1 infection.

Source: Gastroenterology - April 4, 2024 Category: Gastroenterology Authors: Tianxu Liu, Qiyu He, Xinyue Yang, Yuebao Li, Disen Yuan, Qinghui Lu, Tianyu Tang, Guiwe Guan, Liwei Zheng, He Zhang, Changyou Xia, Xin Yin, Guochao Wei, Xiangmei Chen, Fengmin Lu, Lin Wang Tags: Basic and Translational - Liver Source Type: research