Carbon Supported Ru-Ni and Ru-W Catalysts for the Transformation of Hydroxyacetone and Saccharides into Glycol-Derived Primary Amines

We report an efficient catalyst Ru-Ni/AC for the reductive amination of hydroxyacetone into 2-aminopropanol. The catalyst has been reused during 3 cycles demonstrating a good stability. As a prospective study, extension to the reactivity of (poly)carbohydrates has been realized. Despite a lesser efficiency, 2-aminopropanol (9% yield of amines) has been formed from fructose, the first example from a carbohydrate. This was possible using a 7.5%Ru-36%WxC/AC catalyst, composition allowing a one-pot retro-aldol cleavage into hydroxyacetone and reductive amination. The transformation of cellulose through sequential reactions with a combination of 30%W2C/AC and 7.5%Ru-36%WxC/AC system gave 2% of 2-aminopropanol, corresponding to the first example of the formation of this amine from cellulose with heterogeneous catalysts.PMID:38572685 | DOI:10.1002/cssc.202400540
Source: ChemSusChem - Category: Chemistry Authors: Source Type: research