Damage-associated molecular patterns as a mechanism of sevoflurane-induced neuroinflammation in neonatal rodents

CONCLUSIONS: In conclusion, 6 h of sevoflurane exposure induces neuroinflammation through the DAMPs pathway, HMGB-1, and galectin-3. Co-administration of ibuprofen reduced sevoflurane-induced neuroinflammation.PMID:38556956 | DOI:10.4097/kja.23796

Source: Korean Journal of Anesthesiology - April 1, 2024 Category: Anesthesiology Authors: Young-Eun Joe Ji Hae Jun Ju Eun Oh Jeong-Rim Lee Source Type: research