QSAR prediction, synthesis, anticancer evaluation, and mechanistic investigations of novel sophoridine derivatives as topoisomerase I inhibitors

This study provides valuable insights into the design and synthesis of N-substituted sophoridine derivatives with anticancer activity.PMID:38561052 | DOI:10.1016/j.fitote.2024.105921

Source: Fitoterapia - April 1, 2024 Category: Biochemistry Authors: Lin Zhu Yongle Yu Youfu Ma Yenong Shi Jamal Alzobair Hammad Kowah Lisheng Wang Mingqing Yuan Xu Liu Source Type: research