Antimicrobial ‐associated encephalopathy due to ampicillin

Key Clinical MessageBecause the β-lactam ring has a molecular structure similar to that of gamma-aminobutyric acid (GABA) neurotransmitters, it binds to GABA A receptors and inhibits GABAergic transmission, causing AAE. The possibility of antimicrobial-associated encephalopathy should be considered in cases of neurological or psy chiatric symptoms after initiating an antimicrobial regimen.
Source: Clinical Case Reports - Category: General Medicine Authors: Tags: CASE VIDEO Source Type: research