Acute effects of Dantrolene on the mechanical performance of myopathic human hearts

Despite significant progress in pharmacotherapy, ventricular arrhythmia (VA) remains a challenge in heart failure (HF). Use of most conventional anti-arrhythmic drugs is limited by proarrhythmia and/or negative inotropic effects.

Source: Heart Rhythm - April 2, 2024 Category: Cardiology Authors: Praloy Chakraborty, Mahmoud M. Bokhari, St éphane Massé, Mohammed A. Azam, Patrick F.H. Lai, Timothy Liang, Daoyuan Si, Abhishek Bhaskaran, Sheila Riazi, Filio Billia, Kumaraswamy Nanthakumar Source Type: research