Neoadjuvant Chemotherapy in Locally Advanced Sinonasal Teratocarcinosarcoma a Rare Malignancy: An Audit From an Academic Tertiary Care Centre in India

Sinonasal teratocarcinosarcomas (SNTCS) are rare sinonasal malignancies, the incidence of which is less than 1% of all tumors. There is limited data available on SNTCS's, often as case reports and small case series. The management of SNTCS is complicated because of its location, locally aggressive biology, difficulty in achieving complete resection, and limited data on chemotherapy in these malignancies. This audit was performed to understand the role of neoadjuvant chemotherapy (NACT) in SNTCS's, its ability to downstage the disease, achieve complete resection, and impact on long-term survival outcomes.

Source: Clinical Oncology - March 18, 2024 Category: Radiology Authors: Z. Peelay, S. Saha, V. Patil, N. Menon, A. Singh, M. Shah, A. Sahu, A. Ubharay, O.R. Chowdhury, K. Prabhash, V. Noronha Tags: Original Article Source Type: research