[18F]FDG PET/CT Signal Correlates with Neoangiogenesis Markers in Patients with Fibrotic Interstitial Lung Disease Who Underwent Lung Biopsy: Implication for the Use of PET/CT in Diffuse Lung Diseases

Conclusion: Previous work has used [18F]FDG uptake in PET/CT as a biomarker in fILD. Here, we highlight a correlation between angiogenesis and [18F]FDG TBR. We show that MVD is higher for UIP than for non-UIP and is associated with mortality in patients with fILD. These data set the scene to investigate the potential role of vasculature and angiogenesis in fibrosis.

Source: Journal of Nuclear Medicine - April 1, 2024 Category: Nuclear Medicine Authors: Porter, J. C., Ganeshan, B., Win, T., Fraioli, F., Khan, S., Rodriguez-Justo, M., Endozo, R., Shortman, R. I., Hoy, L. R., Maher, T. M., Groves, A. M. Tags: Clinical Investigations Source Type: research