Cutaneous Metastases: Clinicopathologic Study of 30 Patients

Skinmed. 2024 Mar 18;22(1):30-34. eCollection 2024.ABSTRACTCutaneous metastases (CMs) of internal malignancies are uncommon. The breast in women and the lung in men represent the two elective sites of internal malignancies metastasizing to the skin. The aim of this study was to determine the epidemiologic, clinical, and pathologic features of CMs. A retrospective study of the patients diagnosed with CMs over 30 years was conducted. Thirty cases of CMs were enrolled in our study. In 16 cases (53%), the skin metastasis revealed the internal malignancy. The mean age was 66.4 years with sex ratio men/women of 2. CMs were solitary in 18 cases and multiple in 14 cases. The most frequent location was the chest (12 cases), followed by the abdomen (eight cases), the scalp (seven cases), and the arms (six cases). The common sites of primary malignancy were the lungs in men (nine cases) and the breast in women (three cases). Nine out of 30 patients died with an average of 33 months after diagnosis. In our study, the most frequent primary malignancy in men was lung cancer and in women breast cancer. The onset of CMs during the course of internal malignancy worsens the prognosis of the disease.PMID:38494612

Source: Skinmed - March 18, 2024 Category: Dermatology Authors: Anissa Zaouak Wissal Ebdelli Malek Ben Slim ène Wael Smida Achraf Debbiche Selima Ben Jannet Houda Hammami Samy Fenniche Source Type: research