Organic photoelectrochemical transistor based on cascaded DNA network structure modulated ZnIn < sub > 2 < /sub > S < sub > 4 < /sub > /MXene Schottky junction for sensitive ATP detection

In this study, the DNA network formed by the hybridization chain reaction (HCR) detects the target adenosine triphosphate (ATP) by adjusting the surface potential of the new heterojunction of ZnIn2S4/MXene. The formation of DNA network amplifies the detection signal of ATP. Significantly, OPECT biosensor could further amplify the signal, which calculated the gain achieved 103, which is consistent with the gain signal of the previously reported OPECT biosensor. Furthermore, the OPECT biosensor achieved a highly sensitivity detection of the target ATP, which the linear detection range is 0.03 pM-30 nM, and the detection limit is 0.03 pM, and illustrated a high selectivity to ATP. The proposed OPECT biosensor achieved signal amplification by adjusting the surface potential of ZnIn2S4/MXene through cascade DNA network, which provides a new direction for the detection of biomolecules.PMID:38552479 | DOI:10.1016/j.talanta.2024.125992

Source: Talanta - March 29, 2024 Category: Chemistry Authors: Xiaodi Wu Jiayi Cui Qihao Sun Xue Wang Jiahe Chen Yue Liu Jia-Hao Chen Degang Jiang Zhongmin Zhou Hong Zhou Source Type: research