The association of plasma leptin, soluble leptin receptor and total and high-molecular weight adiponectin with the risk of perioperative neurocognitive disorders

Exposure to surgery often comes with a substantial risk of developing perioperative neurocognitive disorders (NCD), particularly in older age. Over 20% of surgical patients can be affected by postoperative delirium (POD) during the first few days after surgery (1). POD is characterized by acute onset of symptoms such as apathy or confusion. Postoperative cognitive dysfunction (POCD) may develop after POD, but may also occur independently (2). Neuropsychological impairment in cognitive domains such as memory or processing speed with new onset after surgery is characteristic of POCD, which is typically transient but can persist months to years.
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Source Type: research