Detection of IgE-autoantibodies to nuclear antigens in patients with systemic sclerosis and analysis of their clinical relevance

CONCLUSIONS: IgE-autoantibodies against CENP-A/B and topo-I occur in SSc underlining the concept that SSc may be a T helper cell type 2 mediated disease. IgE-anti-CENP-A-antibodies correlated with disease activity, but this has to be confirmed in larger studies.PMID:38530662 | DOI:10.55563/clinexprheumatol/s3pvx0
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Authors: Source Type: research