Pulsed Field Ablation: A Promise with Future Broad-based Applicability or a Pause needing Further Analysis

Recent scientific data has positioned pulsed-field ablation (PFA) as a possible replacement for traditional AF ablation approaches delivering radiofrequency or cryoablation thermal energy. PFA uses non-thermal, high-voltage electrical fields applied to cardiac tissue to create nanopores in the cellular membrane that disrupt cellular integrity, resulting in cellular necrosis and irreversible electroporation (IRE).

Source: Heart Rhythm - March 26, 2024 Category: Cardiology Authors: Thomas F. Deering, T. Jared Bunch, Dhanunjaya Lakkireddy, Christopher F. Liu, Jonathan P. Piccini, Anne Marie Smith Source Type: research