Study of the impurity profile of photodegradation in lomefloxacin hydrochloride ear drops using liquid chromatography combined with ion trap/time-of-flight mass spectrometry

CONCLUSIONS: The structural characteristics and fragmentation patterns of the photodegradation impurities were also studied. The study of the photodegradation impurity profile in lomefloxacin hydrochloride ear drops provides a scientific basis for quality control of these ear drops and ensures the safety of drug use by the public.PMID:38525499 | DOI:10.1002/rcm.9732

Source: Rapid Communications in Mass Spectrometry : RCM - March 25, 2024 Category: Chemistry Authors: Hongxia Zeng Ying Yang Jiarui Gao Yuping Zhou Jinqi Zheng Source Type: research