Urinary cytomegalovirus excretion: the unresolved issues

Ann Pharm Fr. 2024 Mar 14:S0003-4509(24)00039-7. doi: 10.1016/j.pharma.2024.03.004. Online ahead of print.ABSTRACTCytomegalovirus (CMV) excretion in urine is frequently observed in clinical practice. However, the specific circumstances and pathophysiological mechanisms underlying this shedding remain largely unknown. Here, we address some of the key questions regarding urinary CMV excretion, focusing on new hypotheses raised by recent advances in the field. Cellular origins of CMV shedding, clinical contexts of occurrence, systemic spread of the virus versus compartmentalization in the urinary tract, and clinical impact are successively discussed.PMID:38492661 | DOI:10.1016/j.pharma.2024.03.004
Source: Annales Pharmaceutiques Francaises - Category: Drugs & Pharmacology Authors: Source Type: research