Feasibility study of radioactivity estimation of 99mTc and 123I-labeled radiopharmaceuticals using shielded syringes

This study investigates the feasibility of estimating the radioactivity of radiopharmaceuticals using shielded syringes. The radioactivities of99mTc-MDP,99mTc-HMDP,99mTc-ECD,99mTc-MAG3, and123I-IMP were measured using a dose calibrator. Correlation coefficients and regression equations were obtained from the radioactivity in the shielded and unshielded syringes.99mTc-MDP was also measured for residual radioactivity after the administration. The correlation coefficients of99mTc-MDP,99mTc-HMDP,99mTc-ECD,99mTc-MAG3, and123I-IMP werers = 0.9998,rs = 0.9997,rs = 0.9999,rs = 0.9998, andrs = 0.9888, respectively. The regression equations werey = 0.0364x + 0.0913,y = 0.0349x + 0.0273,y = 0.0343x − 0.0018,y = 0.0522x + 0.1215, andy = 0.0383x + 0.0058, respectively. The correlation coefficient for the residual radioactivity of99mTc-MDP wasrs = 0.9887 and the regression equation was y = 0.1505x + 0.0853. The radioactivity of99mTc- and123I-labeled radiopharmaceuticals in shielded syringes was accurately measured. It was suggested that the measuring shielded syringes could provide an estimate of the actual radioactivity.

Source: Radiological Physics and Technology - March 22, 2024 Category: Physics Source Type: research