State-of-the-art detection of Mycobacterium tuberculosis in blood during tuberculosis infection using phage technology

World TB Day —a date commemorating the announcement by Koch of a bacterial aetiology for TB—is a chastening reminder of how little the diagnostic landscape has progressed. Culture-based growth of Mtb from disease sites continues to be the gold standard for diagnosis. For pulmonary TB, this is most frequently from spontaneously expectorated sputum. Key benefits of culture include high specificity in the absence of cross-contamination, and the opportunity to determine drug susceptibility of isolates to inform effective therapy.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Perspective Source Type: research