APOE ε4 carriage associates with improved myocardial performance from adolescence to older age

Although APOE ε4 allele carriage confers a risk for coronary artery disease, its persistence in humans might be explained by certain survival advantages (antagonistic pleiotropy).

Source: BMC Cardiovascular Disorders - March 21, 2024 Category: Cardiology Authors: Constantin-Cristian Topriceanu, Mit Shah, Matthew Webber, Fiona Chan, Hunain Shiwani, Marcus Richards, Jonathan Schott, Nishi Chaturvedi, James C. Moon, Alun D. Hughes, Aroon D. Hingorani, Declan P. O ’Regan and Gabriella Captur Tags: Research Source Type: research