Acetyl-CoA synthetase 2 induces pyroptosis and inflammation of renal epithelial tubular cells in sepsis-induced acute kidney injury by upregulating the KLF5/NF- κB pathway

Pyroptosis of the renal tubular epithelial cells (RTECs) and interstitial inflammation are central pathological characteristics of acute kidney injury (AKI). Pyroptosis acts as a pro-inflammatory form of progr...

Source: Cell Communication and Signaling - March 21, 2024 Category: Molecular Biology Authors: Jian Lu, Ya Hou, Si-Xiu Liu, Bo Jin, Jing Liu, Nan Li, Yan Zhu, Qing-Yan Zhang, Cheng Wan, Yuan Feng, Jun Xie and Chun-Ming Jiang Tags: Research Source Type: research