Deletion of Slc9a1 in Cx3cr1+ cells stimulated microglial subcluster CREB1 signaling and microglia-oligodendrocyte crosstalk

Microglial Na/H exchanger-1 (NHE1) protein, encoded by Slc9a1, plays a role in white matter demyelination of ischemic stroke brains. To explore underlying mechanisms, we conducted single cell RNA-seq transcriptom...

Source: Journal of Neuroinflammation - March 20, 2024 Category: Neurology Authors: Shanshan Song, Helena Oft, Shamseldin Metwally, Satya Paruchuri, John Bielanin, Victoria Fiesler, Chaim Sneiderman, Gary Kohanbash and Dandan Sun Tags: Research Source Type: research