Highlights from the literature

Paediatric updates for SPIRIT and CONSORT Setting up and running large multicentre network, randomised clinical trials (RCTs) in child health is hard work, expensive and time-consuming. To run the study within a robust research governance structure is crucial to scientific credibility, usefulness of the results and conclusions of the study, and reduces research waste. Reporting your work accurately and in a comprehensive and transparent way requires a structure and standardisation. So far, the Standard Protocol Items: Recommendations for Interventional Trials (SPIRIT) and Consolidated Standards of Reporting Trials (CONSORT) guidelines are there for you to follow, but these are not child specific. Inadequate reporting continues to be a major challenge to dissemination. Paediatric-specific problems related to RCTs include: (a) omission of key features on trial interventions and outcome measurements in children across the age groups; (b) the description of ethnicity, race and various social determinants of health; (c) sample...
Source: Archives of Disease in Childhood - Category: Pediatrics Tags: Miscellanea Source Type: research